Vitamin E Flashcards

1
Q

T or F
There are only 3 isomers of vitamin E

A

False, many isomers

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2
Q

What is the most biologically active form of vitamin E

A

Alpha tocopherol

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3
Q

What are the two categories of vitamin E?

A

Tocopherols and tocotrienols

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4
Q

Why can not all vitamin E reverse deficiency? Which type is best?

A

All isomers differ in absorption, transport, rentention, and metabolism
Alpha tocopherol is best

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5
Q

What are the active stereoisomers of alpha-tocopherol? Which can reverse deficiencies

A

RRR (reverses deficiency)
RRS
RSR
RSS

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6
Q

What is the RDA for vitamin E for women and men 14-70 years old?

A

Women= 15
Men= 15

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7
Q

What is the RDA for women who are 18 yrs or younger and pregnant? How about 19+?

A

<18= 15
>19= 15

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8
Q

What is the RDA for women who are 18 yrs or younger and breastfeeding? How about 19+?

A

<18= 19
>19= 19

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9
Q

Why is vitamin E susceptible to destruction during food prep/storage?

A

Because it’s fat soluble
(Roasting seeds also destroy)

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10
Q

What are food sources of vitamin E?

A

What germ
Vegetable oils
Nuts
Seeds
Leafy greens
Whole grains (rice bran)
Some breakfast cereal

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11
Q

T or F
Tocopherol is not found free in food

A

False

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12
Q

Maintenance of ____ integrity and ____ membranes and all 8 isoforms being an _____ are the functions of vitamin E

A

Membrane
Lipoproteins
Antioxidant

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13
Q

_____, ____, and ____ are all needed to recycle vitamin E. ____ needs NADH OR NADPH and _____ needs selenium to do this.

A

Vitamin C
Niacin
Glutathione peroxidase

Niacin
Glutathione peroxidase

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14
Q

What processes can vitamin E impact?

A

Inflammation
Blood coagulation

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15
Q

T or F
Vitamin E aids in transcription factors of gene expression, reduces cholesterol metabolism and possibly decreased cell proliferation

A

True

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16
Q

T or F
Vitamin E helps in signal transduction

A

True

17
Q

What 5 vitamin E functions are related to the immune system?

A
  1. Antioxidant
  2. Protecting cell membranes of immune cells
  3. Gene expression
  4. Signal transduction
  5. Anti inflammatory
18
Q

High intakes of vitamin E decrease absorption and metabolism of what?

A

Beta-carotene (fat soluble non nutrient)
Vitamin K

19
Q

T or F
When you increase your omega-3 intake (PUFA) you should decrease your vitamin E intake

A

False, need to increase vit E

20
Q

Where are there higher amounts of vitamin E?

A

Lungs
Brain
Erythrocytes
Mitochondrial membranes
Endoplasmic reticulum

21
Q

A severe deficiency is rare but is more common in individuals with ____, pre-terms,____, fat malabsorption diseases (IBD), and ___

A

Cystic fibrosis
Genetic disorders with lipoprotein production
Adherence to low fat diets

22
Q

Peripheral neuropathy which is ____, myopathy which is ____, and retinopathy which is _____, and hemolytic anemia are all symptoms of a severe vitamin E deficiency

A

Neurological problems
Muscle pain and weakness
Damage to the retina of the eye
Red blood cells getting damaged by oxygen= free radical attack

23
Q

T or F
Vitamin E is one of the most toxic fat soluble vitamins

A

False, one of least toxic

24
Q

More than ____ mg of vitamin E may interfere with vitamin K function

A

> 1000 mg

25
Q

T or F
Vitamin E toxicity may result in mild GI problems such as nausea, diarrhea, or flatulence

A

True

26
Q

1000 mg of alpha-tocopherol= _____ IU alpha-tocopherol

A

1500 IU

27
Q

The UL for alpha tocopherol for adults older than 19 is ____

A

1000 mg/d

28
Q

T or F
In the small intestine vitamin E is put into chylomicrons for transportation in the lymphatic system

A

True

29
Q

T or F
Alpha-tocopherols have different stereoisomeric forms

A

True

30
Q

T or F
Pre-terms mag be low in vitamin E

A

True

31
Q

T or F
Tocotrienols are not found in food naturally

A

False