Immune System Flashcards

1
Q

What are the primary organs of the immune system?

A

Bone marrow
Thymus

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2
Q

What are the secondary organs of the immune system?

A

Spleen
Lymph nodes
GALT (gut associated lymphatic tissue)

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3
Q

The immune system requires energy, ____, _____, healthy micro biome, ____, and non nutrients to function properly

A

Macronutrients
Selected micronutrients
Probiotics/ prebiotics

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4
Q

Where do all immune cells arise and mature?

A

Bone marrow

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5
Q

Where do B cells mature?

A

Bone marrow

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6
Q

Where do T cells mature?

A

Thymus

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7
Q

What are the two parts of the immune system?

A

Innate (natural)
Adaptive (acquired)

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8
Q

Helps enhance the ability of antibodies and phagocyte cells to clear microbes and damaged cells from an organism, promotes inflammation, and attacks the pathogens cell membrane

A

Complement proteins

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9
Q

What type of protein in the blood is mostly synthesized by the liver? What’s an example?

A

Complement protein
Cytokines

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10
Q

What type of protein is synthesized by monocytes, macrophages, and many other cells types

A

Cytokines

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11
Q

What are the types of cytokines and their abbreviation?

A

Interleukins (IL)
Interferons (IFN)
Tumor necrosis factor (TNFa)

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12
Q

What are the pro inflammatory cytokines?

A

Some interleukins (IL-1, IL-1b, IL-2, IL-6)
Interferon
Tumor necrosis factor

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13
Q

What are the anti-inflammatory cytokines?

A

IL-4
IL-10
IL-13

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14
Q

What is the function of the complement protein phagocytosis?

A

Coat intruders
Attack phagocytes

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15
Q

What is the function of complement proteins membrane attack?

A

Rupturing cell wall of bacteria

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16
Q

What is the function of complement proteins inflammation?

A

Attracting macrophages and neutrophil

17
Q

What is the defense reaction of the body against injury that involves redness/ heat, swelling, pain, and impaired body function?

A

Inflammation

18
Q

What type of protein is found in the blood and released in response to inflammation?

A

CRP or C-reactive protein

19
Q

where is CRP synthesized?

A

In liver in response to factors released by macrophages and fat cells

20
Q

Examples of chronic states include type 1 and 2 diabetes, allergies, ____, _____,_____, central adiposity and others

A

Arthritis
Metabolic syndrome
Crohn’s disease

21
Q

T or F
Possible complications of inflammation are CVD, NAFLD, cancer, and dementia

A

True

22
Q

B-lymphocytes are characterized by their ability to produce ____ and they mainly deal with extracellular _____

A

Antibodies
Pathogens

23
Q

What are the 5 major classes of B-cells?

A

IgG
IgA
IgM
IgE
IgD

24
Q

T or F
T cells neutralize toxins/ microorganisms and activate complement proteins

A

False, B cells do that

25
Q

Do T or B cells form a communication between the innate and acquired immune systems?

A

B cells

26
Q

T or F
T-cells can recognize any type of antigens

A

False, can only recognize antigens presented to them

27
Q

What type of cell presents antigens to T-cells?

A

Antigen presenting cell

28
Q

Genetics, ___, exercise, ____,_____,_____, age, smoking, ____, ____, and nutritional status are all factors affecting the immune system

A

Sex
Central adipose
Chronic disease
Breastfeeding
Alcohol
Gut microbiota

29
Q

Which of the following are part of the adaptive immune system?
A. Immunoglobulins
B. Monocytes
C. Granulocytes
D. All correct
E. None correct

A

A

30
Q

T or F
Central adiposity causes chronic low grade inflammation

A

True

31
Q

T or F
Reduced appetite during illness can come from a lack of Zn and Cu

A

False

32
Q

Which of the following are part of the innate immune system?
A. Hydrochloric acid
B. Skin
C. Phagocytes
D. All correct
E. None correct

A

D

33
Q

T or F
The three principle types of T-lymphocytes are cytotoxic T-cells, helper T-cells, and regulator T-cells

A

True

34
Q

What produces antibodies?

A

Plasma B cells

35
Q

T or F
More protein is needed during infection partly due to the increase in production of antibodies and other immune cells

A

True

36
Q

T or F
Humoral immunity represents B and T cells

A

False

37
Q

T or F
Fiber plays no function in the immune system

A

False

38
Q

T or F
The immune system fights parasites, bacteria, and fungi

A

True

39
Q

T or F
Inflammation only has negative effects on the body

A

False