Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Immune Micro 3 > Viruses of childhood > Flashcards

Viruses of childhood Flashcards

1
Q

atypical measles

A

intense rash, vesicles, petechiae, prurpura or urticaria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

erythema infectiosum =

A

parvovirus B19

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

RotaTeq vaccine

A

life attenuate vaccine, human bovine reassortant,

oral, 3xbetween 2, 4 6 months

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

parvovirus B19 complciations

A

anemia due to reduced cell number and hemoglobin

aplastic crisis due to RBC loss

transmission to fetus > still brith, edam (detal hydrops) anemia, CHF, no abnormalities

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

subacute sclerosing panencephalitis

A

measles

CNS perosnality, behavior memory changes

myoclonc jerks, spasticity

blindness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

newly discovered parvovirus resposnible for repiratory and GI infections

A

bocavirus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

parvovirus internalized via

A

coated pits

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

parvovirus B19 clinical

A

eryhtma infectiosum (fifths disease)

red cheeks, maculopapu;ar rash

circulating immune complexes > rash, athralgia, arthritis, but do not fix complement

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

congenital rubella syndrome

A

cataracts

heart defects

deafness

growth + mental retardation

FTT

mortality

microencephaly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

key to meales, mumps, rubella vaccination effectiveness

A

single antigenic type (infection prevents reinfection)

systemic replication prior to infecting target ogan - antibodies can limit or block at this stage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

measles pathogenesis

A

respiration

lymphatic spread > viremia

conjunctivae, respiratory, urinary tract, vessels, lymph, cns

Virus infected endothelial cells plus immune Tcells

Rash

Recovery + immunity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

post measeles encephalitis

A

acute onset of headache, vonfuion, voimitiung, coma after rash dissipates

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

major enterovirus groups resonsible for paralytic disease, encephalitis meningitis, RTI, undifferenciated fever

A

Poliovirus,

coxsackie A and B virus

Echnoviruses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

parvovirus infection location, recepotr

A

actively replicated RBC progenitors in marrow (viremia)

receptor is blood gorup P antigen (globoside)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

antigen group of Rota virus most common cause of human disease

A

group A (VP6 subgroup)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

rubella (german measles) =

A

togavirus

13
Q

targets for norovirus therapy

A

protease, viral pomyerase

structural porteins target for virus like particle Vaccines

15
Q

chicken pox =

A

varcilla zoster virus

16
Q

norovirus reinfection due to

A

lack of lasting immunity, strain diversity

17
Q

enterovirus pathogensis

A

fecal/oral or resp

rplication in oropharynx and GI

viremic phase to target tissue (antibody can block before(

possible secondary viremeia

18
Q

Rotatrix vaccine

A

live attenuated singel human strain

oral 2x 2 and 4 months

19
Q

mumps clinical sypmtoms

A

parotitis

swelling of glands (ochrtitis, mastitis, pancreatitis, throiditis)

CNS involvement

(mild meningitis and rare encephalitis)

20
Q

rare outcomes measles

A

post-infectious encephalitis

subacute sclerosing pnenncephalitis (CNS)

no resolution of acute infection caused by defective CMI (often fatal)

21
Q

entero toxin of rotavirus, role

A

NSP4 - receptor on cells > signaling events lead to increase in intracellular Ca >> tight junction interference

also stimulates enteric nerves > stimulate goblet cells > stmulate Cl release >diarrhea

23
Q

Parvovirus replication requirements

A

host S phase

uses cellular DNA pol

24
Q

rotavirus virology

A

11 ds RNA segements, 12 genes

no envelope

3 layer capsid

multple antigenic groups A E

25
Q

hand foot, mouth disease, viruses and symptoms

A

Coxsackie A and Enterovirus 71

mild fever, sore through

vesicular lesions

fatigue and loss of apeptite

26
Q

MMR measles mumps rebella vaccine

A

live, attenuated combination

blocks virus during systemic stage and prevents infection of target organ

27
Q

symptoms measues

A

cough, conjunctivitis, coryza, photpobia, koplik spots

(otitis media, croup pneumonia, blindness, encephalitis complications)

28
Q

rubella virology

A

togavirus, only infects humans

one serotype

29
Q

adult meningitis symptoms

A

headache

fever chills

nausea vomiting

still meck light sensitiity

30
Q

roseola (exanthem subitum) =

A

human herpes virus 6

31
Q

measles (rubeola) =

A

paramyxovirus

33
Q

parvovirus B19 morphology

A

ss DNA virus

nonenveloped iscosohedral

replicates in nuclues

dependent on host DNA replciation

34
Q

infant symptoms meningitis

A

fever

irritability

poor eating

hard to awaken

35
Q

mumps pathogenesis

A

resp epithelium

local replication and viremia

infection of parotid gland and CNS

inflammation adn swelling > sweeling of other glands

pancrease (associated with juvenile diabetes?)

Immune Micro 3 (17 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions