emerging viruses Flashcards
factors contributing to emergence of new viral diseases
population density, travel, changes in social behavior, environment, industry, changes in microorganisms
emergence of hantavirus due to
increased contact with mice due to rainfall, foodsource, increased mouse population
symptoms, monkeypox
headache, rash, swollen lymph nodes, backache, fatigue > 3 days > crusting, scabbing of > 3 weeks
wild nile and dengue are members of ____ family
flavivirus
transmission dengue (hemmoragic) fever
mosquito to human (urban) or monkey
emergence monkeypox due to
pet choice changes, movement of virus and reservoir into new areas of commerce
second infection, with new dengue virus serotype > Hemmoragic fever and dengue shock syndrome =
non neutralizing antibodies causes macrophage infection > cytokine release. Rupture of vasculature, internal bleeding, palsma loss, shock
diagnosis dengue hemmorhagic fever
postive tourniquet test, immunofluorescence for viral antigen
disease caused by hentavirus
Hentavirus-induced (cardio-)Pulmonary syndrome, leading to pulmonary edema, death
emmergence of West nile and Dengue due to
increased range of vector (dengue) introduction of virus resevoir into new area (westnile)
diagnosis of west nile virus
local WNV activity in area, adults 50 age or older with unexplained encephalatis or meningitis in late summer/fall
arboviral encephalatis transmission
reservoir in birds, arthropod spread between birds, horse or human dead end host
Arbovirus 3- types diseases
fever+macupapular rash, OR encephalatis, OR hemmoragic fever
clinical features west nile fever (severe)
fever, ataxia, myelitis, change in mental status, GI, seizures
incubation time, monkeypox
12 days