Virus Attachment Proteins/Receptors

Question 1

Rhinovirus

Answer 1

Family: Picornaviridae

VAP: VP1-VP2-Vp3 complex

Target Epithelial Cells

Receptor: Intracellular adhesion molecule 1 (ICAM-1)

Question 2

Adenovirus

Answer 2

Family: Adenoviridae

VAP: Fiber Proteins

Question 3

Reovirus

Answer 3

Family: Reoviridae

VAP: alpha-1

Question 4

Rotavirus

Answer 4

Family: Reoviridae

VAP: VP7 & VP4

Question 5

Semliki Forest Virus

Answer 5

Family: Togaviridae

VAP: E1-E2-E3 complex

Question 6

Rabies Virus

Answer 6

Family: Rhabdoviridae

VAP: G protein gp

Target Cell: Neuron

Receptor: Acetylcholine Receptor, neural cell adhesion molecules (NCAM)

Question 7

Influenza A

Answer 7

Family: Orthomyxoviridae

VAP: HA gp

Target Cell: Epithelial Cells

Receptor: Sialic acid

Question 8

Measles Virus

Answer 8

Family: Paramyxoviridae

VAP: HA gp

Question 9

Epstein-Barr Virus

Answer 9

Family: Herpesviridae

VAP: gp350 and gp220

Target Cell: B Cells

Receptor: C3d complement receptor CR2 (CD21)

Question 10

Murine Leukemia Virus

Answer 10

Family: Retroviridae

VAP: gp70

Question 11

Human Immunodeficiency Virus (HIV)

Answer 11

Family: Retroviridae

VAP: gp 120

Target Cell: Helper T cells

Receptor CD4 molecule and chemokines coreceptors

Question 12

Poliovirus

Answer 12

Target Cell: Epithelial

Receptor: Immunoglobulin super family proteins

Question 13

Herpes simplex virus

Answer 13

Target Cells: Many cells

Receptor: Herpes virus entry mediator (HVEA) nectin-1

Question 14

B19 parvovirus

Answer 14

Target Cell: Erythroid precursor

Receptor: Erythrocyte P antigen (globoside)