TLRs Flashcards

1
Q

TLR1

A

Ligand:Triacyl Lipopeptides

Targets: Mycobacteria

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2
Q

TLR2

A

Ligand: Peptidoglycans, GPI-linked proteins, Lipoproteins, Zymosan

Targets: Gram-positive bacteria, Trypanosomes, Mycobacteria, Yeast and other fungi

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3
Q

TLR3

A

Ligand: dsRNA

Targets: Viruses

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4
Q

TLR4

A

Ligand:LPS, F-protein

Targets: Gram-negative bacteria, Respiratory syncytial virus(RSV)

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5
Q

TLR5

A

Ligand:Flagellin

Targets: Bacteria

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6
Q

TLR6

A

Ligand: Diacyl lipopeptides, Zymosan

Targets: Mycobacteria, Yeast and Fungi

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7
Q

TLR7

A

Ligand:ssRNA

Targets: Viruses

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8
Q

TLR8

A

Ligand:ssRNA

Targets: Viruses

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9
Q

TLR9

A

Ligand: CpG unmethylated dinucleotides, Dinucleotides, Herpes virus infection

Targets:Bacterial DNA, Herpes

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10
Q

TLR10,11

A

Ligand: Unknown

Targets:Unknown

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