TLRs Flashcards
1
Q
TLR1
A
Ligand:Triacyl Lipopeptides
Targets: Mycobacteria
2
Q
TLR2
A
Ligand: Peptidoglycans, GPI-linked proteins, Lipoproteins, Zymosan
Targets: Gram-positive bacteria, Trypanosomes, Mycobacteria, Yeast and other fungi
3
Q
TLR3
A
Ligand: dsRNA
Targets: Viruses
4
Q
TLR4
A
Ligand:LPS, F-protein
Targets: Gram-negative bacteria, Respiratory syncytial virus(RSV)
5
Q
TLR5
A
Ligand:Flagellin
Targets: Bacteria
6
Q
TLR6
A
Ligand: Diacyl lipopeptides, Zymosan
Targets: Mycobacteria, Yeast and Fungi
7
Q
TLR7
A
Ligand:ssRNA
Targets: Viruses
8
Q
TLR8
A
Ligand:ssRNA
Targets: Viruses
9
Q
TLR9
A
Ligand: CpG unmethylated dinucleotides, Dinucleotides, Herpes virus infection
Targets:Bacterial DNA, Herpes
10
Q
TLR10,11
A
Ligand: Unknown
Targets:Unknown