13. Intro to Immunology II

Question 1

A microbiologist is studying cells and after test it is show there are notable levels of cathepsin outside the cell. What cell type is this?

A. Eosinophil
B. Neutrophil
C. Basophil
D. Effector T cells 
E. Memory T

RFA

Answer 1

Ans A.- Eosinophil
Inside: basis proteins, cationic protein,neurotoxin

Outside Histaminase, peroxidase, cathepsin

play a major role in parasitic and helminths and allergic reaction

Question 2

Which of these is not true of the thymu?

A. Includes a network of cells with CD14
B. Induces death of T cell that can’t recognized self
C. Place of interaction between CD4 and CD19 cells
D. Function decreases with age
E. Site of maturation for CD4 cells

RFA

Answer 2

ANS. C- place of interaction between CD4( T cells and ) CD19(B Cells ) that is Paracortex of Lymph Nodes

A. CD14 cells are dendritic and monocytes and part of the thymus network

B. Yep that happen

D. yep get worse with age

E. CD4(T cells) mature in the Thymus and get activated in lympnoids.

Question 3

You love histo bc you’re a masochist. You’re looking at a slide under a microscope, and observe pale-staining, constricted nuclei with dark blue to black granules. What CD markers would you find in this type of cell? (MG)

A. CD15 and 45
B. CD 3 and 4
C. CD 16 and 56
D. CD 3 and 8

Answer 3

A. CD15 and 45

basophils are granulocytes

All other choices are actual CD pairings

Question 4

Which of the following is not one of the 4 major groups of dendritic cells? (MG)

A. Lyphoid/plasmacytoid-derived
B. Monocyte-derived/myeloid
C. Langerhans
D. Follicular
E. Surveillance

Answer 4

E. Surveillance

Question 5

A patient presents to you in Sickle Cell Crisis. During physical exam palpation reveals splenomegaly. Failed breakdown of old and defective erythrocytes is due to a dysfunction in which of the following?

A. Marginal Zone 
B. White Pulp
C. Red Pulp 
D.  Medulla
E. Paracortex

SZ

Answer 5

Ans C. Red Pulp

Red pulse is the portion of the spleen that removed old or defective erythrocytes and platelets.

A. Marginal zone is where antigens meet APCs, initiating an immune response.
B. White pulp contains T-cells and B-cells
D. Medulla is the plasma secreting portion of the lymph node.
E. Paracortex is the portion of the lymph node that activates T cells.

Question 6

Your patient tests positive for HIV. This type of specialized dendritic cells are activated by the disease and originate from lymphoid precursors. These cells then give rise to what?

A. DC1 type cells
B. DC2 type cells  
C. Myeloid cells DC
D. Langerhans cells
E. Follicular DC

SZ

Answer 6

Ans. B DC2 type cells

Plasmocytoid dendritic cells originate from lympoid precursors. They give rise to DC2 type cells which deal with viruses.

A. DC1 type cells are folicular DC, Langerhans cells, and myeloid DC cells. They have myeloid precursors and are related to monocytes.