Virology Flashcards
how are viruses different from bacteria?
have small genomes with dna OR rna
have no nuclear membrane or external cell wall
have no intracellular systems
what is viral classification based on?
size/shape
enveloped/naked
RNA/DNA
antigenic differences
what is the capsomere?
protein subunits of the capsid
what is the capsid?
capsomers assembled to surround genome
what is the nucleocapsid?
capsid and genomic nucleic acids
what is the virus envelope?
lipid bilayer taken from host cell membrane that makes virus labile and unable to survive on surfaces
what is the viral life cycle?
attachment
penetration
uncoating
transcription
translation
genome replication
assembly
release
what is the steps of the virus-host cell interacitons?
entry
primary replication
spread
cell/tissue tropism
secondary replication
cell injury or persistence
host immune response
what are the potential consequences of virus-cell interactions?
proliferation and cell lysis
latent infections
persistent infections
oncogenesis
what are prions?
infectious agents made of protein that convert other proteins to their form
what do prions cause?
spongiform encephalitis