Viro1 Flashcards
What is the family of the Monkeypox virus?
Poxviridae
What type of structure does the Monkeypox virus have?
Complex Structure, Enveloped, Linear DS DNA
What is the host range for Monkeypox?
Primate
How is Monkeypox transmitted?
Mechanical transmission by biting arthropods, aerosolized respiratory secretions, introduction into abrasions from fomites
What is the incubation period for Monkeypox?
12 days
What are some virulence factors of the Monkeypox virus?
Virokines, complement binding proteins, interferon resistance, TNF soluble receptor
What are common clinical signs of Monkeypox in humans?
Rash and fever
What diagnostic methods can be used for Monkeypox?
PCR, VI, IHC, EM
What is the lifecycle characteristic of Poxviruses?
Cytoplasmic lifecycle
What are the stages of progression of pox lesions?
Macule, Papule, Vesicle, Pustule, Ulceration, Scab formation, Healing/scar
What is the natural host for Cowpox?
Rodents
How is Cowpox transmitted?
Aerosolized respiratory secretions, direct contact, fomites
What are the clinical signs of Cowpox in cats?
Pox lesions on teats, paws, head, mouth
What preventative measures can be taken against Cowpox?
Disinfection of milking equipment, sanitation, rodent control
What is the host range for Sheeppox/Goatpox?
Sheep, Goats, Cattle
How is Sheeppox transmitted?
Mechanical via wounds, biting arthropods, aerosolized respiratory secretions
What is a significant clinical sign of Sheeppox?
Pox lesions on skin
What is the mortality rate in young animals infected with Sheeppox?
50-100%
What economic impacts can Sheeppox cause?
Damage to hides/leather, decreased milk production
What is the host range for Myxoma virus?
Lagomorphs
How is Myxoma virus transmitted?
Mechanical via biting arthropods, fomites, aerosolized respiratory droplets
What are the clinical signs of Myxoma virus infection?
Raised edematous lesions on skin, conjunctivitis, fever
What is the mortality rate for Myxoma virus in Oryctolagus cuniculus?
50-100%
What is the host range for Swine pox?
Suidae