BacT3 Flashcards

1
Q

What family does Pasteurella multocida belong to?

A

Pasteurellaceae

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2
Q

What is the morphology of Pasteurella multocida?

A

Gram negative rod, facultative anaerobe

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3
Q

Which species are commonly affected by Pasteurella multocida?

A

*Swine: Atrophic rhinitis
*Bovine: BRD
*Rabbits: Snuffles (rhinitis)
*Dogs/Cats: Bite wounds and aspiration pneumonia

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4
Q

What is the primary disease associated with Histophilus somnii in bovines?

A

Bovine respiratory disease complex (BRD)

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5
Q

What type of pneumonia is Actinobacillus pleuropneumoniae associated with in swine?

A

Fibrinous pleuropneumonia

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6
Q

What growth medium is used for cultivating Actinobacillus pleuropneumoniae?

A

Chocolate agar

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7
Q

What is a significant virulence factor of Mycoplasma bovis?

A

No cell wall or peptidoglycan

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8
Q

Fill in the blank: Pasteurella multocida is part of the normal _______ flora.

A

oronasopharyngeal

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9
Q

True or False: Mycoplasma species can be easily cultivated in vitro.

A

False

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10
Q

What is the common clinical sign associated with Actinobacillus lignieresii in cattle?

A

Abscess and granulomas of the tongue (‘Wooden tongue’)

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11
Q

What are the primary clinical signs of Mycoplasma haemofelis infection in felines?

A

*Acute: Fever, pale mucous membranes, lethargy, splenomegaly
*Chronic: Recurrent anemia, weight loss

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12
Q

Which species is the reservoir for Mycoplasma ovipneumoniae?

A

Domestic sheep

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13
Q

What is a common diagnostic method for lower respiratory disease in small animals?

A

*Transtracheal wash (TTW)
*Bronchoalveolar lavage (BAL)
*Postmortem lung samples

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14
Q

What is the primary transmission route for Bordatella bronchiseptica?

A

Airborne transmission and fomites

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15
Q

Fill in the blank: Most common lower respiratory infection in dogs, cats, and horses is _______.

A

Aspiration pneumonia

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16
Q

What is the typical age group affected by Glasserella parasuis?

A

Weaner age group

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17
Q

What is the primary treatment for hemoplasma infections in canines?

A

Doxycycline

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18
Q

What condition does Mycoplasma mycoides subsp. mycoides cause in bovines?

A

Contagious Bovine Pleuropneumonia

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19
Q

What are the common co-infections associated with Mycoplasma bovis?

A

*M. haemolytica
*P. multocida
*H. somnii

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20
Q

What are the key features of the RTX family of toxins?

A

*Glycine-rich amino acid sequence
*Secreted by a T1SS
*Bind to leukocytes and activate neutrophils

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21
Q

True or False: Pasteurella multocida is known to grow well on MacConkey’s agar.

22
Q

What is the role of siderophores in gram-negative bacteria?

A

Iron binding

23
Q

What is the significance of the capsule produced by Pasteurella multocida?

A

Antiphagocytic and poorly antigenic

24
Q

What is the primary method for preventing bovine respiratory disease?

A

Vaccination

25
Fill in the blank: The most common respiratory disease in swine is caused by _______.
Actinobacillus pleuropneumoniae
26
What are the clinical signs of Actinobacillus equuli infection in foals?
Foal is typically lethargic and has high mortality
27
What type of bacteria is Bordatella bronchiseptica?
Gram negative coccobacilli, aerobic, motile
28
What is a key reservoir for Bordatella bronchiseptica?
Infected animals, with asymptomatic carriers being common
29
What are the virulence factors of Bordatella bronchiseptica?
* Pili (fimbriae) for adherence * LPS * Siderophores * Toxins (e.g., adenyl cyclase toxin, tracheal cytotoxin, dermonecrotic toxin)
30
What disease does Bordatella bronchiseptica cause in swine?
Atrophic rhinitis in piglets and weaners
31
Which animal is particularly predisposed to bronchopneumonia caused by Bordatella bronchiseptica?
Dogs, especially brachycephalics
32
What is the primary disease caused by Streptococcus pyogenes in humans?
Streptococcal pharyngitis (strep throat)
33
What is the hemolytic pattern of Streptococcus pyogenes?
Beta-hemolytic
34
What is the role of M-protein in Streptococcus pyogenes?
Binds host fibrinogen and decreases complement activity
35
Which Streptococcus species is associated with mastitis in cattle?
Streptococcus agalactiae
36
What disease is caused by Streptococcus equi subsp. equi in horses?
Strangles (rhinopharyngitis)
37
What is the virulence factor of Rhodococcus equi?
vapA (virulence associated protein)
38
What type of pathogen is Mycobacterium tuberculosis?
Acid-fast, non-spore-forming, human-adapted pathogen
39
What is a significant disease caused by Mycobacterium bovis?
Bovine tuberculosis, which is zoonotic
40
How is Mycobacterium avium subsp. paratuberculosis transmitted?
* Prenatal (in utero) * Postnatal (feces, milk, colostrum)
41
What is the primary clinical manifestation of Johne's disease caused by Mycobacterium avium subsp. paratuberculosis?
Chronic diarrhea and weight loss in ruminants
42
What is the primary diagnostic method for detecting Mycobacterium bovis?
Tuberculin test (skin test)
43
Which species are primarily affected by Mycobacterium avium complex?
Poultry and occasionally small children
44
What is the significance of the caudal fold test in cattle?
It is used for tuberculosis testing
45
What are the clinical signs of canine leproid granuloma complex?
Nodular or ulcerated masses
46
What is the treatment for leprosy caused by Mycobacterium leprae?
Approximately 2 years of antibiotics
47
What type of bacteria is Nocardia and how does it present?
Gram positive, pleomorphic rods; presents with deep tissue infections
48
What is a common complication associated with Streptococcus equi subsp. equi infection?
Purpura hemorrhagica (Type III hypersensitivity reaction)
49
What is the significance of the virulence factor lipoarabinomannan in Rhodococcus equi?
It influences macrophage response
50
What is the primary host for Mycobacterium bovis?
Cattle, but it also affects humans and wildlife