Viral & Bacterial Pathogens of the Haemolymphatic System Flashcards

1
Q

hemolytic infectious anemia is due to

A

direct damage to red cells or increased erythrophagocytosis

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2
Q

Hemorrhagic infectious anemia is typically due to

A

blood-sucking parasites

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3
Q

What are causes of hemolytic anemia in cattle?

A
  • Babesiosis
  • bacillary hemoglobinuria
  • lepto
  • anaplasmosis
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4
Q

What are causes of inadequate production of RBCs causing anemia in cattle?

A
  • Chronic BVDV
  • Johne’s Dz
  • Other chronic infections (e.g enzootic bovine leukosis)
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5
Q

What causes anemia in sheep?

A

Mycoplasma ovis

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6
Q

What causes anemia in pigs?

A

Leptospirosis
Mycoplasma suis

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7
Q

What causes anemia in horses?

A

EIA
Equine ehrlichiosis

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8
Q

What causes anemia in dogs?

A
  • Mycoplasma hemocanis
  • Ehrlichia canis
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9
Q

What causes anemia in cats?

A

FIA
FeLV
FIV

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10
Q

What causes anemia in poultry?

A

Chick anemia virus
Aegyptianella pullorum

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11
Q

Hemorrhage may be caused by…

A

blood loss from parasites
coagulopathy
vasculitis

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12
Q

What may cause hemorrhage in cattle?

A
  • Posterior vena caval thrombosis
  • Mycotoxins
  • Heartwater
  • Anthrax
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13
Q

What may cause hemorrhage in sheep?

A
  • Bacillary hemoglobinuria
  • Bluetongue
  • Anthrax
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14
Q

What may cause hemorrhage in Equines?

A
  • Mycotoxins
  • EVA
  • EIA
  • African horse sickness
  • Anaplasma phagocytophilum
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15
Q

What may cause hemorrhage in dogs?

A
  • leptospirosis
  • infectious canine hepatitis
  • canine monocytic ehrlichiosis
  • canine cyclic thrombocytopenia
  • Rocky mountain spotted fever
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16
Q

What can cause splenomegaly in ruminants?

A
  • Salmonellosis
  • Lymphosarcoma
  • Anthrax
  • Anaplasmosis
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17
Q

What can cause splenomegaly in pigs?

A
  • Salmonellosis
  • African Swine fever
  • Eperythrozoon suis
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18
Q

What may cause splenomegaly in horses?

A

Salmonellosis
EIA

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19
Q

What may cause splenomegaly in cats?

A

lymphosarcoma

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20
Q

What may cause lymphadenitis, lymphangitis, or lymphadenopathy in cattle?

A
  • cutaneous actinobacillosis
  • TB
  • enzootic bovine leukosis
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21
Q

What may cause lymphadenitis, lymphangitis, or lymphadenopathy in sheep?

A
  • Caseous lymphadenitis
  • Tick pyaemia
  • Tularemia
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22
Q

What may cause lymphadenitis, lymphangitis, or lymphadenopathy in equines?

A

Strangles
Tularemia
Strep spp.
Sporotrichosis
Farcy
Ulcerative lymphangitis
Epizootic lymphangitis

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23
Q

What may cause lymphadenitis, lymphangitis, or lymphadenopathy in cats?

A

Feline leukemia
feline plague
tularemia

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24
Q

What is neutrophilia?

A

A response to inflammation with release of reserve neutrophils

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25
Explain chronic neutrophilia.
'Closed cavity' inflammatory process
26
What can cause chronic neutrophilia?
pyometra in dogs traumatic reticuloperitonitis in cattle
27
What can cause extreme neutrophilia?
Hepatazoon canis Leukemia
28
What is the mechanism of leukopenia?
Direct damage to circulating leukocytes affecting bone marrow, lymph nodes, thymus
29
What is a non-specific cause of leukopenia?
Severe bacterial infection, septicemia
30
What causes tick-borne fever in ruminants?
- Anaplasma phagocytophilum
31
What is the vector that causes tick-borne fever in ruminants?
- Ixodes spp.
32
Once a ruminant recovers from tick-borne fever, they remain... but can ... and act as...
remain: carriers can: resist further infections act as: reservoirs
33
What are clinical signs in ruminants for tick-borne fever?
- fever, inappetence, conjunctivitis, milk drop, abortion - immunosuppression
34
What are clinical signs of tick-borne fever in sheep specifically?
louping ill tick pyemia
35
What organism causes equine granulocytic ehrlichiosis?
Anaplasma phagocytophilum (Ehrlichia equi)
36
What are clinical signs of equine granulocytic ehrlichiosis?
Fever listlessness limb edema petechiae icterus Ataxia
37
What disease in dogs can have neutrophilia &/or leukopenia?
Parvovirus
38
What disease(s) in cats can have neutrophilia &/or leukopenia?
Feline panleukopenia FIV FeLV
39
What tissues are affected by feline panleukopenia?
Bone marrow thymus lymphoid tissue
40
What are some causes of leukosis/lymphoproliferative disease in cattle?
Enzootic bovine leukosis due to bovine leukemia virus (Deltaretrovirus)
41
What are clinical signs of enzootic bovine leukosis?
enlarged LN Weight loss Drop in milk production Variable signs depending on site of tumor
42
How do you diagnose enzootic bovine leukosis?
Lymphocytosis Pathology Serology: AGID, ELISA Sporadic lymphosarcomas?
43
What can cause leukosis/ lymphoproliferative disease in cats?
Feline leukemia/sarcoma virus FIV
44
What are the four subgroups of FeLV?
FeLV-A: transmitted naturally, replication competent FeLV-B: arises through recombination FeLV-C: arises through mutation FeLV-T: arises through genetic insertion & resulting change to envelop protein
45
Where does the FeLV reside?
in saliva, urine, feces, milk
46
What condition is required for transmission of FeLV?
close contact
47
What are clinical signs of FeLV?
Fever, lymphadenopathy Symptomless period
48
What type of non-neoplastic FeLV causes immunosuppression?
FeLV-T
49
What type of non-neoplastic FeLV causes anemia?
FeLV-C
50
What are clinical signs of non-neoplastic FeLV?
immunosuppression anemia enteritis reproductive failure
51
What are clinical signs of neoplastic FeLV?
lymphoid/lymphosarcoma myeloid thymic lymphoma, T-cell
52
What are causes of Leukosis/ leukemia in poultry?
Avian leukosis Marek's Disease
53
Caseous lymphadenitis is caused by...
Corynebacterium pseudotuberculosis
54
Tick pyemia is caused by...
Staph aureus
55
Tick-borne fever is caused by...
Anaplasma phagocytophilum
56
Bacillary hemoglobinuria is caused by...
Clostridium hemolyticum
57
Feline infectious anemia is caused by...
Mycoplasma hemofelis Hemobartonella felis
58
Strangles is caused by
Streptococcus equi
59
Tuberculosis is caused by...
Mycobacterium bovis
60
Rocky Mountain spotted fever is caused by...
Rickettsia rickettsii
61
Heartwater is caused by...
ehrlichia ruminantium
62
Canine monocytic ehrlichiosis is caused by...
Ehrlichia ewingii
63
Canine cyclic thrombocytopenia is caused by...
Anaplasma platys
64
Plague is caused by...
Yersinia pestis
65
Tularemia is caused by...
Francisella tularensis
66
Anthrax is caused by...
Bacillus anthracis
67
Glanders is caused by...
Burkholderia mallei
68
What fungi affect the hemolymphatic system?
Sporothrix schenkii Histoplasma farciminosum
69
What viruses affect the hemolymphatic system?
Feline leukemia virus feline immunodeficiency virus Avian leukosis Marek's disease Gumboro disease Chick anemia virus Enzootic bovine leukosis EIA African horse sickness bluetongue virus