vasculitis Flashcards
classification types
size vessel, ANCA +, hyptersensitivity
large vessel types
giant cell arteritis, takayasu arteritis, kawasaki
giant cell arteritis
presents as elderly with headache, Large/med vessels. international elastic intimal, granulomatous/giant cells
takayasu arteritis
presents in young asian women» pulseless arms. looks the same as giant cell, large vessels
kawasaki
presents in children, first acute mucosal swelling then cardiac, aneurysm. medium vessles
ANCA types
polyarteritis nodosa (PAN), Microscopic polyangitis, eosinophilic granulomatous polyag (churg straus), granulomata with polyangiitis (Wegner)
Polyarteritis nodosa
hep B, painful cutaneous nodules, infarction, multi organ systems. Path- small/med, systemic, necrotizing, seclusion/dilation
which are P anca
all besides wegners
which are C anca
wegners (GwP_
microscopic polyangiitis
clinically like Werner but less lung involvement, small vessels, no granulomas,
eosinophlic granulomatous polyangiitis-
history of bad asthma, small vessels, granulomatous, eosinophils in blood/tissue
granulomata with polyangiitis
C anca! respiratory infections, saddle nose, pulm nodules with cavitation, renal, path. small necrotizing granulomas, tissue inflam
hypersensitivity types
henoch schelein Purpura, cyroglobulinemic vasculitis
Henoch Schelein Purpura
raised palpable purpura, blood in storm renal, penile/scrotal, path: small
cyroglobulinemic vasculitis
chronic hep c. small vessels. cryoglobulin precipitates in blood when cold