RA Flashcards

1
Q

most common

A

chronic inflam disease

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2
Q

cause is

A

unknown

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3
Q

epidemiology

A

women, 40-70, gingivitis, RF factor/anticitrillium, 1st degree FH, HLA DR4

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4
Q

diag

A

6 weeks symptoms, morning stiff >1 hr, 3+ joints swelling, symmetric, RA nodules, RF,

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5
Q

extra articular symtpms

A

lungs, renal, cardiac, ocular (Scleritis), servical spine

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6
Q

Polymyalgia Rheumatica

A

inflammation, 50+, bursa/tendon pain, treat with steroids, risk for temporal arteritis,

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7
Q

disease progression

A

unknown> inflam> RF factors/immune complex> synovitis attack cartilage and bone

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8
Q

early synovium

A

hyperplastic, hypertrophic, fibrillar, T cells, proteinases

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9
Q

late synovium

A

Mphage, ILB, TNF, lymphocytes, T cells, CD4 helper cells, angiogenesis, panes, eroded bone

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