fibromyalgia Flashcards
clinical
diffuse pain, stiff, fatigue, mood, sleep, normal labs/ no obvious swelling (subjective to the patient)
associated condition s
IBS, headache, TMG, allergy, mitral valve prolapse
fibro epi
syndrome, 5% general pop, females 20-60, stress is a trigger
pathophys
unknown, genetic, pain processing
pain processing in fibro
less serotonin (anti pain) and more subsance P (pro pain). also affect sleep/depression
treat fibro
educate, confirm pain, treat depression
repetitive injury
overuse, tendinopathy not tendinitis, chronic degenerative changes, pain with tendon loading, injury.exercise, flouroquinonlones
pronociceptive
NMDA glutamate, substance PNK
antinociceptive
norepinephrine, serotonin, GABA, opioids