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rheumatology > vasculitis > Flashcards

vasculitis Flashcards

1
Q

types of vasculitis affecting small vessels

A

HSP
Churg-Strauss syndrome
microscopic polyangiitis
Wegener’s granulomatosis

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2
Q

types of vasculitis affecting medium vessels

A

polyarteriris nodosa
churg-strauss syndrome
kawasacki disease

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3
Q

types of vasculitis affecting large vessels

A

giant cell arteritis

takayasu’s arteritis

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4
Q

churg-strauss syndrome AKA

A

eosinophillic granulomatosis with polyangiitis

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5
Q

wegner’s granulomatosis aka

A

granulomatosis with polyangiitis

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6
Q

general featrues

A 
purpura
joint + muscle pain 
peripheral neuropathy 
renal impairment
GI disturbance
hypertension

fever, fatgiue, weight loss, anaemia

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7
Q

Tests

A

CRP and ESR

ANCA**

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8
Q

p-ANCA aka

A

anti-MPO

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9
Q

P-ANCA - what vasculitis

A

microscopic polyangitis

churg-strauss syndrome

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10
Q

c-ANCA aka

A

anti-PR3

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11
Q

c-ANCA - what vasculitis

A

wegener’s granulomatosis

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12
Q

usual Mx

A

steroids (oral, IV, inhaled)
and
immunosuppresants

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13
Q

ex of immunosuppresants used

A

cyclophosphamide
methotrexate
azathioprine
rituximab

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14
Q

HSP

A

IgA vasculitis
usually purpuric rash lower limbs of kids

inflammation due to IgA deposits

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15
Q

HSP triggers

A

URTI e.g. tonsilitis

gastroenteritis

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16
Q

HSP - classic features

A

purpura
joint pain
abdo pain
renal involvement - IgA nephropathy

17
Q

HSP Mx

A

supportive w analgesia and hydration

18
Q

Eosinophilic Granulomatosis with Polyangiitis - what does it affet

A

lung and skin

19
Q

Eosinophilic Granulomatosis with Polyangiitis - features

A

severe asthma

elevated eosinophil levels on FBC

20
Q

microscopic polyangiitis features

A

renal failure
SOB
haemoptysis

21
Q

Wegner’s granulomatosis - areas it affecs

A

resp tract

kidneys

22
Q

Wegner’s granulomatosis - features

A 
epistaxis
crusty secretions
hearing loss
sinusitis
saddle shaped nose
cough
wheeze
haemoptysis
glomerulonephritis
23
Q

Wegner’s granulomatosis - classic sign

A

saddle shaped nose due to perforated nasal septum

24
Q

Polyarteritis Nodosa - assoc w

A

hepatitis B

can also occur without clear cause, with HepC, with HIV

25
Q

Polyarteritis Nodosa - areas it affects

A

skin
GIT
kidneys
heart

26
Q

Polyarteritis Nodosa - features

A

renal impairment
strokes
MI
livedo reticularis

27
Q

Kawasaki disease - features

A 
persistent high fever >5 days
erythematous rash 
bilateral conjuncitivits
erythema and desquamation palms+ soles
strawberry tongue
28
Q

Kawasaki disease - key complication

A

coronary artery aneurysm

29
Q

Kawasaki disease - Mx

A

aspirin

IVIg

30
Q

takayasu’s arteritis

A

mainly affects aorta

vessels and their branches can become narrowed and blcked

31
Q

takayasu’s arteritis presentation

A

fever
malaise
arm claudication syncope

32
Q

takayasu’s arteritis Ix

A

CT or MR angiography

rheumatology (26 decks)

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