sjogren's syndrome Flashcards

1
Q

what

A

autoimmune condition affecting exocrine glands

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2
Q

symptoms

A

dry mucous membranes

  • dry eyes
  • dry mouth
  • dry vagina
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3
Q

primary sjogren’s

A

condition occurs in isolation

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4
Q

secondary sjogren’s

A

occurs related to SLE or rheumatoid arthritis

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5
Q

assoc antibodies

A

anti-Ro

anit-La

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6
Q

schirmer test

A

folded peice of paper uner lower eyelid, left for 5 min and distance of moist mesures

tears should travel 15mm
<10mm is significant

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7
Q

Mx

A

artificial tears and saliva
vaginal lubricants
hydroxychloroquine

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8
Q

complications

A

eye infections - conjuncitivits, corneal ulcers
oral problems - dental cavities, candida
vaginal - candidiasis, sexual dysfunction

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9
Q

affects on other organs (rare)

A
pneumonia
non-hodgkin's lymphoma
peripheral neuropathy 
vasculitis
renal impairment
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