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rheumatology > granulomatosis with polyangitis > Flashcards

granulomatosis with polyangitis Flashcards

1
Q

features

A 
URT - epistaxis, sinusitis, nasal crusting 
LRT - dyspnoea, haemoptysis
rapidly progressive glomerulonephritis
saddle shape nose deformity 
vasculitis rash 
cranial nerve lesions
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2
Q

autoantibodies

A

cANCA

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3
Q

Ix

A

CANCA positive
CXR - cavitating lesions
renal biopsy

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4
Q

renal biopsy shows

A

epithelial crescents in Bowman’s capsule

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5
Q

Mx

A

steroids
cyclophosphamide
plasma exchange

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rheumatology (26 decks)

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