passmed misc Flashcards
azathioprine may cause…
myelosuppresion
is azathioprine safe in pregnancy
yes
ankylosing spondylitis xray findings
subchondral erosins
sclerosis
squaring vertebrae
cautions to sulfasalazine
G6PD deficiency
allergy to aspirin or sulphonamides (cross-reactivity)
essential test prior to starting biologics for RA
CXR to look for TB
–> they can cause reactivation
drug induced SLE - autoantibodies
anti-histone antibodies
what should be avoided in eldery patients taking warfarin
NSAIDs
- risk GI haemorrhage
patient’s with sjogrens are at increased risk of
lymphoma
polyarteria nodosa is assoc with…
hepatitis B
antiphospholipid syndrome Mx
primary thromboprophylaxis - low dose aspirin
2ry thromboprophylaxis
- warfarin with INR 2-3
- recurrent VTE - warfarin with INR 3-4
diffuse cutaneous sclerosis affects where predominantly
trunk and proximal limbs
giant cell arteritis is assoc with what aortic pathology
aortic aneurysm
gout x-ray findings
normal joint space
soft tissue swelling
periarticular erosions
confirming Dx of antiphospholipid syndrome
1+ of the antibodies present in plasma on 2 occasions 12wks apart
monitoring required with leflunomide
BP - baseline and at each review
CRP in SLE
usually normal (in contrast to ESR)
osteoporosis in man - which blood test
testosterone
side effect colchinine
diarrhoea
azathioprine + allopurinol
severe interaction causing bone marrow suppression
hydroxychloroquine effect on eyes
may result in severe + permanent retinopathy
SLE - type of hypersensitivity reaction
type 3
blood tests results in osteoporosis
normal
most common cause septic arthritis
staph a = overall most common cause
gonorrhoea most common cause in young sexually active adults
raised CRP in someone with SLE
underlying infection
