gout Flashcards
1
Q
what
A
crystal arthopathy assoc w chronically high uric acid levels
2
Q
gouty tophi
A
subcutaneous depostis of uric acid
3
Q
presentation
A
single acute hot, swollen painful joint
gouty tophi
4
Q
important differential
A
septic arthritis
5
Q
typical joints
A
base of big tow - MTP joint
wrists
CMC joint
6
Q
diagnosis
A
aspiration of fluid
must exclude septic arthritis
7
Q
aspirate fluid will show
A
needle shaped crystals
negatively birefrringegent
monosodium urate crystals
8
Q
x-ray will shw
A
lytic lesions
punche out erosions with sclerotic bordrs and overhanging edges
9
Q
Mx - acute flare
A
- NSAIDs
- colchicine
- steroids
10
Q
Mx - prophylacis
A
allopurinol
lifestyle - loose weight, miminise alchohol
11
Q
allopurinol
A
xanthine oxidase inhibitor
dont initiate until after acute flare settled
12
Q
risk factors
A
male obesity high purine diet alcohol duiretics CVD or kidney disese FHx
