Vascular infections Flashcards

1
Q

Bacteraemia + symptoms/signs of infection =

A

bloodstream infection

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2
Q

Types of bacteraemia

A
  • Transient
  • Intermittent
  • Continuous
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3
Q

Transient bacteraemia =

A

number of bacteria slowly increasing in the blood

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4
Q

Intermittent bacteraemia =

A
  • Appear and reappear in the blood

- Pneumonia, pyelonephritis, abscess, meningitis

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5
Q

Continuous bacteraemia =

A
  • Number of bacteria in blood same and continuously detected
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6
Q

Intravascular catheter-related bloodstream infection (CRBSI) routes of colonisation

A
  • At time of insertion = whole area will be bright red
  • Via hub contamination = point where other drips are attached – can migrate down lumen of line
  • Haematogenous
  • Via infusion = at entry of catheter in skin – area will be infected
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7
Q

Main bacteria that cause CRBSI

A
  • Coagulase negative staphylococci - 31%

- Staphylococcus aureus -20%

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8
Q

Diagnosis of CRBSI

A
  • Patient with an intravascular catheter and systemic signs of infection
  • Differential time to positivity > 2 hours
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9
Q

Infective Endocarditis presentation

A
  • Non-specific illness = lethargy, malaise, night sweats, anorexia, weight loss
  • Heart failure = SOB, orthopnoea, PND
  • Results of extra-cardiac foci of infection = back pain from HVO, stroke, abdominal pain from splenic infarct
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10
Q

Infective Endocarditis aetiology

A
  • 34% = staphylococci

- 32% = Sterptococci

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11
Q

Infective Endocarditis management

A
  • flucloxacillin (6 hourly – 4-6 weeks)

- Surgery on valves, drain pus, remove infected devices

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12
Q

Mycotic aneurysm definition

A
  • Aneurysms resulting from, or secondarily infected by, microorganisms
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13
Q

Mycotic aneurysm presentation

A
  • Usually systemic symptoms of infection and variable symptoms from aneurysm
  • Painless swelling or painful swelling
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14
Q

Mycotic aneurysm aetiology

A
  • Salmonella spp
  • Staphylococcus aureus
  • Streptococcus spp
  • Pseudomonas aeruginosa
  • Escherichia coli
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15
Q

Infected DVT presentation

A
  • Symptoms/signs of DVT and systemic infection and/or respiratory symptoms (when infected thrombus breaks from DVT travels via the venous system to the lungs – infected pulmonary emboli)
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16
Q

Infected DVT aetiology

A
  • Depends on mechanism but commonly S. aureus, streptococci and anaerobes in IVDU
17
Q

Infected DVT diagnosis

A
  • 3 blood cultures

- Confirmation of DVT plus exclusion of other causes

18
Q

DVT’s and bacteria

A
  • DVTs can be seeded with bacteria during bacteraemia or directly e.g. IVDU injecting into femoral vein leads to a seeds femoral DVT