Fungal pathogens Flashcards
properties of fungi
- Eukaryotic
- Single celled to macroscopic
- Reproduce asexually + sexually with spores
What are the growth forms of fungi
Hypha - Moulds
Yeast cells - yeasts
What are the 3 lifestyles of fungi
- Saprophytes - decaying organic matter
- Plant pathogens
- Animal pathogens
What are the 3 type of fungal disease
- Superficial infection - skin, hair, nails etc
- Subcutaneous infection - subcutaneous tissue
- Systemic infection - deep-seated organs affected
What are dermatophytes
Group of moulds causing superficial infections
- originate in soil, animals or humans
Athletes foot
Tinea pedis
- Typical cause Trichophyton rubrum
- itching, flaking, dry skin
Fungal nail infection
Tinea unguium
- Typical cause Trichophyton rubrum + T.interdigitale
- Thickening, discolouring, dystrophy
Jock itch
Tinea cruris
- Typical cause T.rubrum
- Itching, scaling, erythematous plaques
Scalp ringworm
Tinea capitis
- Mainly seen in pre-pub children
- scaly patches, black dots, severe inflammation
What are Kerion celsi
Inflamed lesions usually from zoophilic dermatophytes
Ringoworm
Tinea corporis
- Typical cause zoophilic/anthropophilic dermatophytes
- Circular erythematous plaques
- May invade follicle
What is topical antifungal therapy + 3 examples
Used for mild diseases
- Terbinafine
- Clotrimazole
- Miconazole
How to treat tinea capitis?
Use systemic oral antifungals such as Griseofulvin, terbinafine, itraconazole
What is Pityriasis versicolor
- Hyper/hypo pigmented lesions
- between puberty and middle age
What is Malassezia
- Genus of yeasts
- part of normal skin flora in humans
- Causes Pityriasis versicolor