vaccination Flashcards
medical microbiology: recall the basic principles of medical microbiology and it's clinical relevance
1
Q
4 ways bacteria avoid host defences
A
resist complement, resist antibodies, resist phagocytosis, inhibit IC killing
2
Q
how do bacteria resist complement
A
thick cell wall (M. tuberculosis); capsule (N, meningitidis)
3
Q
how do bacteria resist antibodies
A
protease (S. pneumonia); antigenic variation (N. gonorrhoeae)
4
Q
how do bacteria resist phagocytosis
A
polysaccharide capsule (N, meningitidis); debilitate phagocytes (Y. pestis); hide inside other cells (Chlamydia)
5
Q
how do bacteria inhibit IC killing
A
escape from phagosome (L. monocytogenes); block phagosome maturation (M. tuberculosis)