vaccination Flashcards

medical microbiology: recall the basic principles of medical microbiology and it's clinical relevance

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1
Q

4 ways bacteria avoid host defences

A

resist complement, resist antibodies, resist phagocytosis, inhibit IC killing

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2
Q

how do bacteria resist complement

A

thick cell wall (M. tuberculosis); capsule (N, meningitidis)

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3
Q

how do bacteria resist antibodies

A

protease (S. pneumonia); antigenic variation (N. gonorrhoeae)

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4
Q

how do bacteria resist phagocytosis

A

polysaccharide capsule (N, meningitidis); debilitate phagocytes (Y. pestis); hide inside other cells (Chlamydia)

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5
Q

how do bacteria inhibit IC killing

A

escape from phagosome (L. monocytogenes); block phagosome maturation (M. tuberculosis)

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