vaccination Flashcards
list examples of bacterial and viral infections for which vaccination can be a successful strategy
what type of vaccine is given to elderly for influenza
inactivated or HA subunit
what type of influenza vaccine is cold adapted so can be administered intranasally
live attenuated FluMist
what vaccine is needed for complete end of polio
inactivated salk followed by oral
what is the live attenuated vaccine for polio
sabin
what type of vaccine is used for rotavirus
live attenuated
what type of vaccine is used in HepB
cloned recombinant (surface antigen)
what type of vaccine is used for pappilomavirus and give 2 examples
virus-like particles from recombinant coat proteins; Gardasil, Cervarix
how are ebola vaccines created
other viruses e.g. chimpanzee adenovirus used to produce vectored vaccine that expresses ebola G protein (protein cloned into other viruses)
7 properties of a good vaccine
stimulates effective immune response, safe and no adverse reactions, stable, inexpensive, easy to administer, simple for authorities to control, substantial benefit to health at low cost and risk
direct protection vs herd immunity
direct: prevent single individual infection; herd: prevent organism from passing between individuals (unvaccinated but uninfected)
3 components of a vaccine
antigen, adjuvant (enhance and modulate immune response), excipients (maintain pH, osmolarity and stability)
types of vaccine available up to 1 year
DTaP-Hib-IPV, MenB, MenC, pneumococcal conjugate, Hib, MMR (+booster)
what does the DT in DTaP-Hib-IPV vaccinate against
diptheria and tetanus toxoids
what does the aP in DTaP-Hib-IPV vaccinate against
whooping cough; acellular vaccines used so fewer adverse reaction
what does the Hib in DTaP-Hib-IPV vaccinate against
haemophilus influenzae type b which causes meningitis and septicaemia (conjugate)
