bacterial properties and disease Flashcards
pathophysiology: explain the pathophysiology of sepsis
1
Q
define sepsis
A
systemic inflammatory response syndrome and infection
2
Q
features of systemic inflammatory response syndrome
A
temperature below 36C or above 38C, tachycardia, high respiratory rate, high white blood cell count
3
Q
define severe sepsis
A
sepsis and organ hypoperfusion (no function despite adequate fluid resiscitation and maintaining blood pressure)
4
Q
severity of sepsis caused by pathogens
A
gram +ve > gram -ve > fungi
5
Q
in sepsis, what does the release of pathogens cause
A
activation of complement pathway
6
Q
complications of sepsis
A
organ dysfunction, multi-organ failure, ischaemic tissue (lactic acidosis), acute tubular necrosis
