fungal infection

Question 1

how are mycoses classified

Answer 1

level of tissue affected (skin: superficial, cutaneous, subcutaneous; systemic: deep)

Question 2

superficial mycoses: which area is affected and consequence on response

Answer 2

skin/hair shaft, so as no living tissue invaded there is no cellular response

Question 3

superficial mycoses: M. globose as example

Answer 3

produces oleic acid which causes inflammation of stratum corneum, leading to dandruff

Question 4

cutaneous mycoses: dermatophytes as example

Answer 4

produce keratinases to hydrolyse keratin; inflammation caused by host response to by-products

Question 5

cutaneous mycoses: ringworm (Tinea) as example

Answer 5

T. capitis: disfigures scalp, common in paediatrics; T. pedis: athlete’s foot; T. corporis

Question 6

subcutaneous mycoses: result of traumatic implantation of fungus

Answer 6

chronic, localised infections of skin and subcutaneous tissue

Question 7

subcutaneous mycoses: what vector does Sporotrichosis use

Answer 7

cat

Question 8

subcutaneous mycoses: what is Mycetoma related to

Answer 8

blast wounds

Question 9

2 types of deep mycoses

Answer 9

primary, opportunistic

Question 10

define primary deep mycoses

Answer 10

able to establish infection in normal healthy host

Question 11

define opportunistic deep mycoses

Answer 11

require immunocompromised host to establish infection

Question 12

deep mycoses: Candida albicans type and what does it colonise

Answer 12

opportunistic, colonise skin, fingernails, tracts

Question 13

deep mycoses: Candida auris resistance

Answer 13

resistant to some antifungal drugs

Question 14

deep mycoses: Aspergillus sp. invade what

Answer 14

kidney, liver, heart