bacterial properties and disease Flashcards

infectivity and virulence: explain the concepts of infectivity and virulence, and define the term infective dose

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1
Q

define infectivity

A

ability to be transmitted to host, to colonise, replicate and evade immune response all while finding a unique niche (inside or outside cells)

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2
Q

define virulence

A

features to enhance disease causation e.g. toxin production, interruption of host processes and degradation of host molecules

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3
Q

define infectious dose

A

number of bacteria needed to cause infection, depending on route of entry, replication speed, tropism, ability to colonise and immune evasion (pathogens with killing, subversion of, phagocytes or immune system have a much lower infective dose)

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4
Q

define pathogenicity

A

ability to cause disease

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5
Q

describe true pathogens

A

affects all individuals

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6
Q

descibe opportunistic pathogens

A

affects immunocompromised or weakened immune system

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7
Q

describe commensal bacteria

A

do not cause disease

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