UW 9 Flashcards
Ovarian tumors and markers
GEDECE
Granulosa: Inhibin (precusios puberty or breast enlargement and vaginal bleeding in peri/post menopausal
Epithelial: CA-125
Dysgerminoma: LDH +/- B-hCG. Adolescents. Fried egg
Embryonal: AFP and B-hCG (very agressive, young children)
Choriocarcinoma: B-hCG.
Endodermal sinius/yolk: AFP (very rare, seen in adolescents)
Light criteria for pleural efusion
Determine if pleural fluid is exudative by meeting at least one of Light’s criteria:
Pleural fluid protein / Serum protein >0.5
Pleural fluid LDH / Serum LDH >0.6
Pleural fluid LDH > 2/3 * Serum LDH Upper Limit of Normal
A quick estimate would be if proteins or LDH are over half of serum value
pH:
Transudate: 7.4-7.55
Exudate: 7.30 - 7.45
Management of TTP
Plasma exchange (removes patient plasma ans replaces it with donor plasma, also remove antibodies against ADAMTS 13 glucorticoids, rituximab
Post transplant infections
<1month: bacterial infection related to operation, wound infection
1-6 months: opportunistic infections en the setting of high dose immunosopresants. Aspergillus, CMV, Mycobacterium
> 6 months: communiti aquire infections at a higher rate then regular people
Amoxicylin and EBV
maculopapular rash 24 hrs after taking medication in the setting of mononucleosis type illnes
Management of mild drug hypersensitivity reaction
Type 1 hypersensitivity
IgE mediated
Trear with antihistamines
Pain control in patients with opioid addictions
Severe pain can be treated with opioids. Follow up carefully to watch out for relapse
Normal duration of QT
<100msec (<0.1seg)
TCAs overdose
seizure, coma, cardiotoxicity (QT >100), hyperpirexia, respiratory depresion with dilated pupils (vs. opiods, miosis )
Role of Ca gluconate in hyperkalemia
Stabilize membrane. It DOES NOT lower potasium
Hyperkalemia treatment
C BIG K
Calcium gluconate
Beta 2 agosnist (not in MI/angina patients). Bicarbonate
Insuline+glucose
Conditions associated with autism (3)
Rett sd
Tuberous sclerosis
Fragile X
Sings and symptoms of peripheral artery aneurysm
Pulsatile mass below de inguinal ligament
Thigh pain do to nerve compression
2nd most common peripheral aneurysm after popliteal
NSAIDs use during 1st trimesters
Gastroschisis
Hypercalcemia mechanism in granulomatosis
increased 1a-hydroxylase activity causes incresed production of 1,25 vitamin D.
Hypercalciuria more common than hypercalcemia in sarcoidosis
