Step3 30 Flashcards
Vaccines that contain egg
Wich ones
Recommendation
Influenza
Yellow fever
Personal or family history of egg allergy is not a contraindication
If an anaphylactic reaction to egg.. administer the vaccine in the hospital setting
If the patient has minor cold symptoms, can you administer immunizations?
YES
First step in HIV in post-exposure prophylaxis if the patient refuses to get tested, results are pending or HIV status is unknown
Start treatment
Stop after the result is negative or continue for 4 weeks if tolerated
Necrotizing fasciitis presentation and classification
Hx of minor skin trauma
Pain out of proportion, swelling, erythema,
Systemic symptoms: fever, hypotension
Type 1: Usually seen in patients with underlying diabetes and PAD S. aureus Bacteroides: crepitus E. coli S. pyogenes Clostridium: crepitus Pseudomonas: immunocompromised
Type II: occur in individuals with no current medical illness.
S. pyogenes is the most common organism
Management of necrotizing fasciitis
Hemodynamic support
Antibiotics
Piperacillin/Tazobactam: S. pyogenes and anaerobes
Vanco: S. aureus including MRSA
Clynda: added to inhibit toxin formation
Erythrasma vs. intertrigo
Erythrasma: Corynebacterium minutisimun Well defined borders or thing plaques with fine wrinkling Fusidic acid cream Clindamycin solution Benzoyl peroxide
Intertrigo
Candida
Erythematous plaques, satellite papules, and significant inflammation
Topical antifungals: miconazole, nystatin, terbinafien
Approach to sicca symptoms
What’s the gold standard?
Dry eyes, dry mouth
Confirm secretory deficiency: eg. Shirmer test (slit lamp to assess tear break up time)
Anti Jo/Anti La
ANA
Rheumatoid factor
The gold standard is salivary gland biopsy. Reserve for young patients with severe symptoms
Treatment of xerostomia alone
Initial treatment is with salivary stimulation
Mechanical or topical
Diagnosis of Autosomal Dominant Polycystic Disease
Renal ultrasound
Family hx but unknown genotype:
18-39: >3 cyst uni or bilateral
40-59: >2 in each kidney
>60: >4 in each kidney
Unknown family history:
Multiple (>10 cysts) in each kidney regardless of age
Genetic testing: usually saved for patients where US does not yield a diagnosis
Management of Autosomal dominant polycystic kidney disease
Aggressive control of risk factors CV and CKD
ACEI preferred for hypertension
Statins
Renal transplant or hemodialysis if end-stage renal disease
Extra external features of Autosomal dominant polycystic kidney disease (6)
Cerebral aneurysms
Liver and pancreatic cyst
Colonic diverticula
Ventral and hinguinal hernias
Aortic regurge
Mitral prolapse
Laboratory findings of polymyalgia rheumatica
ESR >40 (sometimes >1000)
Elevated CRP
+/- Anemia
20% normal
Clinical presentation of polymyalgia rheumatica
Age >50
Bilateral pain and morning stiffness >1 month
>2 of the following Neck or torso Shoulder or proximal arms Proximal thigh or hips Constitutional: fever, malaise, weight loss
Treatment of polymyalgia rheumatica
Steroids
Low dose for pain
High dose for giant cell artheritis
(absence of response indicates another diagnosis is possible)