urological problems and the kidney Flashcards

1
Q

what is nephrolithiasis ?

A

formation or the disease of stones in the kidneys

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2
Q

what are the risk factors for developing urinary stones ?

A

male
white
obese
diabetic

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3
Q

what are the conditions associated with urinary stone disease ?

A

primary hypertension
sarcoidosis
CF

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4
Q

what is the nature of the pain associated with urinary stones ?

A

acute colicky flank pain radiating to the groin

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5
Q

what are the required workup for urinary stones ?

A

rule out medication induced stones
CT can be used
MRI if the patient is pregnant
urine culture to identify the type of stone

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6
Q

what are the different types of urine stones/crystals ?

A
calcium oxalate 
calcium phosphate 
uric acid 
struvite 
cystine
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7
Q

what are the associated conditions with calcium oxalate crystals ?

A

hypercalciuria

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8
Q

what are the associated conditions with calcium phosphate crystals ?

A

distal renal tubular acidosis

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9
Q

what are the associated conditions with uric acid crystals?

A

hyperurecemia
gout
DM
obesity

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10
Q

what are the associated conditions with struvite crystals ?

A

alkaline crystals due to chronic urinary tract infection

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11
Q

what are the associated conditions with cystine crystals ?

A

cystinuria

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12
Q

what is the most important intervention when it comes to treatment of renal stones ?

A

markedly increase fluid intake

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13
Q

what can be given in cases of hypercalciuria ?

A

thiazide diuretics

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14
Q

what can be given in cases of hyperuricosuria ?

A

allopurinol or potassium citrate

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15
Q

what can be given for hypocitraturia ?

A

potassium citrate

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16
Q

what size of stones should pass spontaneously ?

A

less than 4 mm

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17
Q

when is urological intervention required ?

A

evidence of :

  • infection
  • acute kidney injury
  • intractable nausea or pain
  • stones that fail to pass
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18
Q

what are the urological intervention options ?

A

shock wave lithotripsy
percutaneous nephrolithotomy
rigid and flexible ureteroscopy

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19
Q

which urological intervention can be used for proximal ureteric stones ?

A

shock wave lithotripsy

20
Q

when is percutaneous nephrolithotomy indicated ?

A

anatomic abnormalities such as horse shoe kidney

21
Q

what is the treatment of choice for middle and distal ureteric stones ?

A

rigid and flexible uterescopy

22
Q

what are the classifications of UTIs in adults ?

A
asymptomatic bacteriuria 
acute uncomplicated cystitis in females 
recurrent cystitis in females 
acute uncomplicated pyelonephritis in females 
complicated UTI
23
Q

what is asymptomatic bacteriuria ?

A

presence of uropathogens without any evidence of systemic infection

24
Q

which group of people are at a much higher risk at acquiring acute uncomplicated cystitis ?

A

sexually active women mostly between the ages of 15-45 y/o

25
what is the most common causative organism of uncomplicated UTI ?
e.coli | staph aureus
26
who is at risk of a complicated UTI ?
- post menopausal women - males - patients with structural or functional abnormalities of the urinary tract - catheters in situ - patients with comorbidities ( DM)
27
what may asymptomatic bacteriuria in young children indicate ?
underlying vesicoureteral reflux
28
what is the clinical picture of uncomplicated cystitis in females ?
acute onset of dysuria frequency suprapubic pain or new urine incontinence
29
what are the differential diagnosis of uncomplicated cystitis in females ?
vaginitis urethritis
30
what are the investigations for uncomplicated cystitis ?
urine analysis : heamturia common inn UTI but not vaginitis/urethritis bacteruria required for a definitive diagnosis urine cultures are not indicated
31
in a case of suspected uncomplicated cystitis if the urine analysis showed negative for pyuria what would that suggest ?
strongly suggests an alternative diagnosis
32
what must be considered if there is a recurrence of attacks within 1 to 2 weeks in recurrent acute cystitis?
consider infection with ab-resistant antibiotic obtain urine culture treat according to culture
33
if there is recurrence within 2 weeks to 6 months of initial infection what is the next best step in management ?
use a different antibiotic
34
if recurrence occurs after 6 months of the initial infection what is the next best thing to do ?
use the same antibiotic
35
what is the clinical presentation of pyelonephritis ?
fever chills costophrenic angle pain nausea and vomiting pyuria is almost always present
36
what investigations should be done in cases of pyelonephritis ?
urine cultures
37
what is the most important factor in the development of catheter associated bacteriuria ?
the duration of the catheterization
38
what are the complications of long term catheterization ?
bacteremia antibiotic resistance flora cystitis/pyelonephritis catheter obstruction
39
what is the clinical picture of catheter associated bacteriuria ?
asymptomatic
40
when do we give antibiotics in UTI ?
only in symptomatic cases to avoid antibiotic resistant bacteria
41
what can we do to reduce the incidence of symptomatic UTI in patients with spinal cord injury ?
hydrophilic-coated catheter
42
what is the pathogenesis of prostatitis ?
reflux of infected urine from the urethra into the prostatic duct
43
what is the treatment fro prostatitis ?
fluoroquinolone
44
what should the broad spectrum ab given in UTI cover ?
staph aureus
45
what is emphysematous pyelonephritis ?
fulimant necrotizing life threatening form of acute pyelonephritis
46
how should the efficacy of treatment be evaluated ?
urine culture