updated hypernatremia Flashcards
what are the causes of hypernatremia ?
either fall unddeer waterr loss or salt gain
if the causes of hypernatremia and hyponatremia are the same what differentiates them ?
if the patient drinks enough water - it’s hyponatremia
if the patient doesn’t drink enough water - hypernatremia
at what level of sodium is the patient considered to have hypernatremia ?
above 145
what is. thr presentation of hypernatmia ?
either
acute : CNS symptoms , confusion ,headache, nausea and vomiting , seizured, coma
chronic : usually asymptomatic
what ar the causes of water loss that ccan causee hypeernatremia ?
insensible losses - sweating, burns, fever
gastrointeestinal loss - vomiting, diarrhea
renal loss - polyuria duee to osmotic diuresis, diabetes insipidus
what are the causees of osmotic diuresis ?
DKA
diureticcs
what are the types of diabetes insipidus ?
central diabetes insipidus : ADH release by the posterior pituitary
nephrogenic diabetes insipidus : normal release of ADH but with a decreased rrenal tubules response
what is thee effect of ADH ?
reabsorbs water in the distal convoluted tubules
whilst aldosterone in the proximal convoluted tubule
what are the causes of sodium gain that cause hyprnatremia ?
primary hyperaldosteronism
cushing syndrome
what are the diseases that cause sodium gain and hence hypernatremia ?
conn’s syndrome - due to tumor in the adrenal cortex, an increase in aldosterone
cushing syndrome - increase in cortisol
what is the electrolyte imbalance that happens in conn’s syndrome and cushing syndrome ?
hypernatremia
hypokalemia
metabolic alkalosis
what are the common causes of nephrogenic diabetes insipidus ?
lithium
sickle cell disease
chronic kidney disease
what is tthe treatment for hypernatremia ?
if the cause is due to water loss - then increase water intake by giving 5% dextrose orr orall water and then treat the cause
what is the treatment for central diabetes insipidus ?
give vasoprressin
what would be the treatment for sodium gain associated with hypernatremia ?
diuretics
and then increase water intake by giving 5% dextrose or oral water
then threat the cause