neuromuscular disease

Question 1

what are the main types of anterior horn cell disease ?

Answer 1

primary disease of motor neurons

spinal cord pathology

Question 2

what disease fall under primary disease of motor neurons?

Answer 2

MND
ALS
poliomyelitis

Question 3

what diseases fall under spinal cord pathology ?

Answer 3

spinal cord infarction

syringomyelia

Question 4

UMN and LMN ?

Answer 4

ALS

Question 5

pure UMN ?

Answer 5

primary lateral sclerosis

Question 6

pure LMN ?

Answer 6

progressive muscular atrophy

Question 7

how to differentiate between bulbar and pseudo bulbar ?

Answer 7

tongue depressor test

Question 8

what medication can be given for MND ?

Answer 8

riluzole

Question 9

what are the single causes of mixed UMN and LMN signs?

Answer 9

freds- fredrich ataxia 
tabby- taboporesis 
cat - cervical spondylosis 
seeks - subacute combined degeneration of the cord 
mice - motor neuron disease

Question 10

what could be the cause of subacute combined degeneration of the cord ?

Answer 10

B12 deficiency

Question 11

what could be the cause of taboporesis ?

Answer 11

syphillus

Question 12

what is cauda equina syndrome ?

Answer 12

severe type of spinal stenosis and the symptoms include sciatica on both sides. weakness or numbness in both legs along with numbness around or under your genitals, or around your anus

Question 13

what are myotomes ?

Answer 13

muscles supplied by spinal cord

Question 14

what is the most common example of hereditary sensory and motor neuropathy neuropathy ?

Answer 14

charcot marie tooth

Question 15

what are the types of charcot marie tooth ?

Answer 15

type 1 which is demyelinating

type 2 which is axonal

Question 16

what type of disease is guilliane barre ?

Answer 16

an autoimmune demyelinating disease

Question 17

what is the chronic form of GBS ?

Answer 17

CIDP
chronic inflammatory demyelinating polyradiculopathy
>8 weeks frrom onset

Question 18

what is the nature of pain in small fibre neuropathy ?

Answer 18

painful and burning sensations nerve conduction is usually normal

Question 19

what is the most common nerve affected in DM ?

Answer 19

Cranial mononeuropathy III

Question 20

what is the disease course like in CIDP ?

Answer 20

relapsing remitting

Question 21

what is the genetic abnormality in CMT ?

Answer 21

PMP22 gene duplication

Question 22

what is the weakness like in CMT ?

Answer 22

progressive distal weakness

Question 23

what is Gullian barre syndrome often precipitated by ?

Answer 23

infection such as viral or campylobacter , post vaccination

aw ay 7aga respiratory or GIT

Question 24

what is the presentation in gullian barre ?

Answer 24

Progressive ascending symmetrical limb weakness (usually starting with the lower limbs)
Lower back pain due to radiculopathy
Paraesthesia, often preceding motor symptoms
lower motor neeuurron signs

Question 25

what can be done to treat GBS ?

Answer 25

IVIg

Question 26

what type of neuromuscular disease does lyme disease cause ?

Answer 26

non compressive radiculopathy

Question 27

what is the presentation of Charcot marie tooth disease ?

Answer 27

onset is usually at puberty , starts with affection of the feet then makes its way to thee hands
champagne bottle legs
pes cavus
claw hand

Question 28

what are the signs of LMNL ?

Answer 28

hypotonia
flaccid paralysis

Question 29

what is miller fisher syndrome ?

Answer 29

one of the forms of GBS and is associated with anti-GQ1B antibodies

Question 30

what is usually found in the CSF of patients with GBS ?

Answer 30

Albuminocytologic dissociation

Question 31

fasiculations are characteristic of which level of affection ?

Answer 31

AHC

Question 32

diurnal variation associated with which level of affection ?

Answer 32

NMJ