Urogenital System I Flashcards

1
Q

what forms most of the urogenital system

A

intermediate mesoderm (+ urogenital sinus

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2
Q

What does UGS stand for

A

urogenital sinus

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3
Q

what is UGS formed from

A

endoderm

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4
Q

is the urogenital system bilateral

A

yes

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5
Q

most of the urogenital ridge is composed of ____

A

nephrogenic cord

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6
Q

the urogenital ridge is not just in what region

A

sacral

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7
Q

where does urogenital region extend

A

from cervical to sacral region

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8
Q

how many kidneys form

A

3 separate kidneys form

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9
Q

how many kidneys remain

A

only 2 out of the 3 that are formed remain

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10
Q

what forms all 3 kidneys

A

intermediate mesoderm

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11
Q

the urogenital ridge grows and buldges into what

A

intraembryonic/coelomic cavity b/w parietal and visceral lateral plate mesoderm

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12
Q

when does 1st kidney form

A

week 4

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13
Q

what is 1st kidney called

A

pronephros

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14
Q

where is 1st kidney located

A

cervical region

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15
Q

when does pronephros kidney degenerate

A

week 4 (degenerates as soon as it forms)

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16
Q

why does the 1st kidney even form if it regenerates right away

A

want the nephric duct

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17
Q

what does the nephric duct form

A

it is like a seed that helps form the 2nd kidney’s drainage system

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18
Q

what is the name of the 2nd kidneys drainage system

A

mesophrenic duct

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19
Q

what is the 2nd kidney called

A

mesonephric kidney

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20
Q

the uteric bud comes off what

A

mesoneric duct

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21
Q

in fmelaes what happens to mesonephric duct

A

all degenerates

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22
Q

in males what happens to mesonephric duct

A

most degenerates ecpet small part that is for reproductive tract (ductus deferens)

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23
Q

What is the other name of the mesophenric duct

A

wolffian duct

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24
Q

99% of efferent ductules do what

A

degenerate

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25
Q

what happens to some mesonephric efferent tubules in males

A

turned into connecting rete testis and epididymis of ductus deferens

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26
Q

when does metanephric kidney form

A

5th week

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27
Q

what is another name for the definitive kidney

A

metanephros

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28
Q

where does the metanephric kidney directly come off of

A

mesonephric duct

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29
Q

what is the little bud off of the mesphenphric duct

A

uteric bud

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30
Q

where do the nephrons connect

A

metanephric blastema

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31
Q

what does uteric bud form first

A

renal pelvis

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32
Q

what is the final branch that is formed in kidney called

A

collecting duct

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33
Q

what is the specific structure that sends signals to form the metanephric blastema to form nephrons

A

collecting duct

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34
Q

when does nephron form

A

week 10

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35
Q

what forms all epithelial excretory tubules leading from bowman’s capsule

A

metanephric cap

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36
Q

all the nephrons are formed from what

A

intermediate mesoderm

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37
Q

what is glomerului formed from

A

VLPM (all blood vessels are!)

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38
Q

when is kidney functional

A

10th week

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39
Q

in 10th week what is filtering the blood

A

maybe a very small amount is kidney, mostly the placenta filters the blood still

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40
Q

nephrons are continuously formed until when

A

birth

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41
Q

are there increase in number of nephrons after birth

A

no

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42
Q

what part of nephron will divide after birth

A

collecting tubules

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43
Q

where in the body are kidneys formed

A

sacral region by bladder

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44
Q

when do kidneys ascend from sacral to lumbar region

A

week 6

45
Q

as it ascends how does the kidney rotate

A

90 degree medial rotation

46
Q

where will the kidney often get stuck

A

inferior mesenteric artery (they pass b/w umbilical arteries)

47
Q

if arteries ascent is blocked will kidneys be functional

A

yes

48
Q

what artery initially supplies the kidney

A

lateral sacral artery, common iliac, aortic bifurcation, arota

49
Q

what are accessory renal arteries

A

they go right into lower lobe of kidney

50
Q

where do true renal arteries go

A

through hilum

51
Q

are accessory renal arteries common?

A

yes, twice as common as accessory renal veins

52
Q

if both kidneys get stopped at IMA what happens clinically

A

horseshoe kidney

53
Q

What happens in pancake kidney

A

upper ends fuse together

54
Q

what parts fuse together in horseshoe kidney

A

lower poles fuse

55
Q

what fuses in pancake kidney

A

upper poles

56
Q

What is renal agenesis

A

onen or both kidney absent

57
Q

if uteric buds don’t grow, collecting ducts and nephrons don’t develop, what results

A

renal agenesis

58
Q

what is one thing that can happen if there is unilateral renal agenesis

A

olighydraminos

59
Q

bilateral renal agenesis is always

A

fatal

60
Q

renal agenesis is often associated with what other birth defects

A

absence of vagina, uterus, ducturs deferens, etc.

61
Q

what is hydronephrosis

A

Dilatation of renal pelvis (*) and calices (major and minor) due to obstruction in the urinary passages resulting in major kidney damage depending if its acute or chronic

62
Q

If there is an extra renal artery what pole of kidney does it usually go to

A

lower pole

63
Q

what can accessory renal artery do to ureter

A

push on it an dimpinge

64
Q

extra renal artery could cause what b/c it pushes on ureter

A

hydronephrosis and damaging kidney

65
Q

uteric bud migrates from mesonephric duct into what

A

urogenital sinus (upper part)

66
Q

what does uteric bud form

A

collecting duct

67
Q

why does uteric bud migrate away from mesonephric duct

A

mesonephric duct will degenerate

68
Q

what does the upper part of urogenital sinus form

A

bladder

69
Q

ureter is formed from what

A

intermediate mesoderm

70
Q

is bladder part of urinary system embryologically

A

no - part of hindgut

71
Q

what forms inside and outside of hindgut

A

endoderm inside

visceral laterl plate mesoderm outside

72
Q

what does uteric bud form from

A

intermediate mesoderm

73
Q

describe double ureter

A

duplicated unilaterally or bilaterally

may or may not be associated witht he duplication of kidney next to median umbilica ligament

74
Q

does double ureter cause problems

A

no, just need a pipe going into bladder

75
Q

what is an ectopic ureter

A

ureter may open into vagina, urethera, or vestibule and usually due to faulty development of mesonephric (wolffian) duct

76
Q

can there be two uteric buds

A

yes

77
Q

if there are two uteric buds going into same sea of mesoderm what will happen

A

duplex ureter

78
Q

what is duplex ureter

A

splitting of ureteric bud duplicating collecting portion of kidney

79
Q

what are the consequences of duplex ureter

A

nephrons poorly developed

80
Q

what are the consequences of duplex ureter

A

nephrons poorly developed

81
Q

what is original of urinary bladder

A

endoderm - part of hindgut

82
Q

what are three parts of urogenital sinus

A

upper
middle
lower

83
Q

upper part of urogenital sinus forms what

A

bladder

84
Q

what comes off upper part of bladder

A

urachus

85
Q

what is function of urachus

A

holds up the upper part of the bladder

86
Q

what is urachus connected to

A

median umbilical ligament

87
Q

where does the ureter directly come off of?

A

mesenephric duct

88
Q

where does the ureter directly come off of?

A

mesenephric duct

89
Q

utereter is formed fromw hat

A

intermediate mesoderm

90
Q

primtiive bladder is lined with what

A

endoderm

91
Q

initially the bladder is endoderm and

A

intermediate mesoderm

92
Q

final the bladder is

A

endoderm only

93
Q

middle of urogenital sinus helps form what

A

prostatic and membranous urethra in males and entire urethra in females

94
Q

last part of urogenital sinus forms what

A

spongy urethra in males and vestibule of vagina in females

95
Q

what is middle of urogenital sinus lined with

A

endoderm

96
Q

what is last part of urogenital sinus lined with

A

endoderm

97
Q

lining of glans penis is lined with what

A

ectoderm (exception!)

98
Q

where does primitive urogenital sinus come from

A

cloacyl

99
Q

where does anal rectal columns end

A

pectinate or dentate line

100
Q

lateral folding failure - which leads to lumen of bladder being exposed on surface of body is called what

A

ectopia vesicae/exstrophy of bladder

101
Q

what else can be associated with ectopia vesicae in males

A

epispadias ((urethra opens on dorsum of penis)

102
Q

outer coretex developes from what

A

intermediate mesoderm

103
Q

when does outer cortex of suprarenal gland form

A

6 week

104
Q

inner medulla develops from what

A

neural crest cells

105
Q

what is a perimesonephric duct formed from

A

intermediate mesoderm

106
Q

what is a perimesonephric duct formed from

A

intermediate mesoderm

107
Q

does mesonephric duct directly form nephron

A

no

108
Q

what directly forms nephron

A

intermediate mesoderm or collecting duct

109
Q

what directly forms seminiferous tubules

A

intermediate mesoderm