Urinary Tract Infections 3 Flashcards
what are some features of congenital syphilis
- stromal haze due to interstitial keratitis
- Hutchinson’s teeth
- saddle nose
“strawberry cervix”
trichomoniasis
tissue destruction and lesions seen in syphilis infections is due to ________
patient’s immune response to the infection
coating of fibronectin to protect against phagocytosis is part of the pathogenesis of _______
syphilis infection
________ can facilitate the perivascular infiltration of syphilis
hylauronidase (“spreading factor”)
in addition to syphilis , _______ (STD) can also disseminate into the lymph nodes and bloodstream
gonorrhea
of the two serological tests for syphilis: non treponemal and treponemal test, which one is used mainly for screening?
non treponemal; measure antibodies against a cardiolipin-cholesterol lecithin antigen
_______ serological test measures antibodies against T. pallidum
treponemal
Haemophilus ducreyi is a gram ______ aerobic/anaerobic rod
gram negative anaerobic rod;
can see “rail road” track like appearance on histology
describe the lesions caused by H. ducreyi
soft, PAINFUL ulcer of the genital region and can usually see painful unilateral buboes
what are the virulence factors of H. ducreyi
- outer membrane serum resistance protein
- two toxins: 1. cytolethal distending toxin (CDT) and 2. hemolysin which both contribute to tissue destruction
the gold standard for diagnosis of H. ducreyi is ______
culture; (cannot do direct microscopy)
Muller Hinton agar with Vancomycin and CVA (cephalothin, vancomycin and amphotericin B)
chancres in syphilis are soft/hard and painful/painless
hard and painless
what is a requirement for growing mycoplasma genitalium or other causes of non gonococcal urethritis in an agar?
must add cholesterol to the growth media because the external membrane contains sterol;
mycoplasma DOES NOT HAVE a cell wall
M. genitalium adleeres to tissues via _____
MgPa tip adhesins
