Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

DEN 7101F - Human Structure and Function > Urgent Review - Exam 2 > Flashcards

Urgent Review - Exam 2 Flashcards

1
Q

Irreversible reaction of TCA cycle/pace setting enzyme

A

Citrate synthase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Citrate synthase function

A

Oxaloacetate + acetyl to form citrate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Citrate synthase activity is dependent on:

A

Oxaloacetate and acetyl CoA concentration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Citrate synthase is inhibited by:

A

High level of citrate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Isocitrate dehydrogenase is an enzyme of:

A

TCA cycle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Isocitrate dehydrogenase stimulated by:

A

ADP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Isocitrate dehydrogenase inhibited by:

A

NADH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

a-ketoglutarate dehydrogenase is inhibited by

A

Succinyl Coenzyme A (competes for CoA)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

If energy charge is high in TCA cycle:

A

oxaloacetate goes to glucose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

If energy charge is low in TCA cycle:

A

oxaloacetate replenishes the citric acid cycle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

NADH carries protons and electrons to

A

NADH-CoQ reductase (Complex 1)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

NAD+ is derived from

A

niacin B3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

NAD+ accepts

A

1 hydrogen and 2 electrons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

FAD+ is derived from

A

riboflavin B2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

FAD accepts

A

2 hydrogen ions and 2 electrons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

____ is an activated carrier of electrons for reductive biosynthesis

A

NADP+

17
Q

Coenzyme A vitamin precursor

A

Pantothenate B5

18
Q

Tetrahydrofolate vitamin precursor

A

Folate

19
Q

Reactive group of coenzyme A

A

Terminal sulfhydryl

20
Q

2 things that occur in liver mitochondria

A

Ketone body formation, urea cycle

21
Q

High ATP causes ____ to be allosterically inhibited and lowers affinity for fructose-6-p

Activated by AMP (low energy signal)

A

Phosphofructokinase

22
Q

Which steps in glycolysis make ATP

A

Phosphoglycerate kinase to form 3PG
Pyruvate kinase to form Pyruvate (last step)

23
Q

Which step in glycolysis uses ATP

A

Hexokinase to make G6P

24
Q

gluconeogenesis - conversion of pyruvate to PEP requires

A

Biotin

25
Q

Steps of pyruvate conversion into PEP

A
  1. Pyruvate carboxylase converts pyruvate into Oxaloacetate
  2. OAA converts to malate
  3. malate leaves mitochondria into cytosol
  4. malate converts into OAA
  5. PEP carboxykinase turns OAA into PEP
26
Q

Regarding PFK2, insulin causes ____ to phosphorylate/dephosphorylate _____

A

Phosphoprotein phosphatase 1 (PP1); dephosphorylates PFK2 to activate the KINASE activity

More F-2,6-BP
More PFK1 activity
More glycolysis

27
Q

Regarding PFK2, glucagon causes ____ to phosphorylate/dephosphorylate _____

A

cAMP dependent protein kinase A; phosphorylates to turn on PHOSPHATASE activity

More F6P
More gluconeogenesis
Less glycolysis

DEN 7101F - Human Structure and Function (23 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions