Exam 1 9/20 Howard Muscle Flashcards

1
Q

endomysium

A

reticular fibers and basal lamina; surrounds each muscle cell

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2
Q

perimysium

A

collagenous CT; surrounds fascicles of muscle fibers

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3
Q

Epimysium

A

dense irrecular collagenous CT; surrounds entire muscle

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4
Q

A band

A

dark

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5
Q

I band

A

light

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6
Q

Z disk or line

A

bisects I band

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7
Q

H band

A

pale area of A band

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8
Q

M line

A

center of H band

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9
Q

Sarcomere measured by

A

z disk to z disk

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10
Q

____ along length of alpha helix actin

A

Nebulin (may assist a-actinin anchor thin filaments to z disk)

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11
Q

Tropomyosin

A

in groove of helix

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12
Q

Troponin attached to:

A

tropomyosin

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13
Q

TnT

A

binds to tropomyosin

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14
Q

TnC

A

binds Calcium

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15
Q

TnI

A

inhibits actin myosin interactions
(helps inhibition of myosin binding to actin by keeping tropomyosin in place)

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16
Q

Myosin molecule

A

2 heavy chains 2 light chains

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17
Q

Titin

A

2500 kD, forms elastic lattice that anchors thick filaments to Z disks

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18
Q

a-Actinin

A

anchors plus end of thin filament to z disk

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19
Q

Myomesin; C protein found:

A

at M band in the middle of H bandW

20
Q

Where do t tubules lie

A

in the plane of A-I junction

21
Q

___ narrows during contraction

A

I band

22
Q

____ dissapears during contraction

A

H band

23
Q

____ get closer during contraction

A

Z lines

24
Q

____ remains unchanged during contraction

A

A band

25
Q

Types of cardiac muscle

A
  1. atrial muscle fiber
  2. ventricular muscle fiber
  3. specialized muscle fiber
26
Q

Cardiac muscle where is nucleus

A

central oval nucleus occasional binucleate

27
Q

Cardiac cell junction forms

A

intercalated disk

28
Q

2 types of intercalated disks

A

transverse, lateral

29
Q

Transverse disks

A

mechanical junctions, fascia adherens (thin filaments attach, can act as z disks)

30
Q

lateral disks

A

electrical connections, gap junctions

31
Q

Atrial Natriuretic peptide found in:

A

atria muscle cells

32
Q

Atrial Natriuretic peptide function

A

lowers blood pressure, decreases ability of renal tubes to resorb water and sodium

33
Q

Differences in T tubules

A

Skeletal: A-I junction, dilated terminal cisternae, triad
Cardiac: t-tubule 2.5x larger, diad, diads at z disk, SR terminals approximate t tubules

34
Q

Smooth muscle does not have

A

striations

35
Q

____ is fusiform

A

smooth muscle

36
Q

Smooth muscle how many nuclei

A

just 1

37
Q

True or false; smooth muscle does not have t tubules

A

true

38
Q

Most common type of smooth muscle

A

unitary - do not contract independently, gap junctions shared between contiguous cells, nerve supply shared

39
Q

Multiunit smooth muscle

A

contract independently, unique nerve supply (their own)

40
Q

Caldesmon

A

present in thin filaments of smooth muscle, same job as tropomyosin (blocks active site of f-actin)

41
Q

Smooth muscle is not:

A

striated

42
Q

Dense bodies that act as Z disks are called

A

interwoven array

43
Q

Smooth muscle myosin heads lined up as:

A

along all molecules not tail to tail

44
Q

Cork screw nucleus occurs in:

A

smooth muscle

45
Q

Increase in muscle mass from:

A

increase in size of muscle fiber