Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

T's Histopathology Y5 > Upper GI Pathology > Flashcards

Upper GI Pathology Flashcards

1
Q

histo of the oesophagus

A

submucosal glands but no goblet cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what is the z line

A

in esophagus when strat sq cells > col epi

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

histo of the body/fundus of the stomach

A

col epi
chief cells -> pepsin
parietal cells -> acid + IF
no goblet cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

histo of the pylorus/antrum of the stomach

A

col epi
neuroendocrine cells -> gastrin
no goblet

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

histo of the duodenum

A

col epi with goblet cells

2:1 villous:crypt ratio

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

histo of oesophagitis

A

redness/inflam

GORD + ulceration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

changes seen in barrets oesophagus

A

strat sp replaces with col epi -> columnar lined oesophagus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what might barrets oesophagus progress to

A

intestinal metaplasia (goblet cells in oesophagus)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

histo of SCC of oesophagus

A

lower 2/3

Keritin + IC bridges

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

histo of adenocarcinoma of oesophagus

A

lower 1/3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

association of oesophageal cancer

A

SCC - asso with smoking/alcohol/achalasia

adeno - asso with barrets

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

cause of gastritis

A

H.pylori bind to epi in stomach and inject toxins with cag A prot

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what may chronic gastritis progress to

A

MALT - B cells driven

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

when does erosion become a gastric ulcer

A

when erosion goes beyond the mucosa and into the submucosa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what should happen to all gastric ulcers

A

Biopsied to exclude malig

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

complications of gastric ulcers

A

bleeding -> anaemia/shock

perforation -> peritonitis

17
Q

most common type of gastric cancer

A

95% = adenocarcinoma

18
Q

histo of intestinal gastric cancer

A

v well differentiated, large mucin-containing glands

19
Q

histo of diffuse gastric cancer

A

poorly differentiated, no glands, composed of single cells

20
Q

what are the antibodies in coeliac disease

A

endomysial ab

tissue transglutamase ab

21
Q

what are the diagnostic investigations for coeliac disease

A

2x duodenal biopsies
1 on a gluten rich diet -> villous atrophy
1 on a gluten free diet -> normal villi

22
Q

what is the histo of coeliac disease

A

villous atrophy, crypt hyperplasia, inc intraepithelian lymphocytes

23
Q

what are the complications of coeliac

A

T cell lymphoma, MALToma, hyposplenism, osteoporosis

T's Histopathology Y5 (22 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions