Histopath fundamentals Flashcards

1
Q

what are neutrophils responsible for and how do the look

A

acute inflam

multilobed and granulated (pink and purple)

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2
Q

what are macrophages responsible for

A

late acute inflam - phagocytic

chronic inflam - become secretory

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3
Q

what are lymphocytes and plasma cells responsible for

A

chronic inflam

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4
Q

what does a lymphoma look like

A

sheet of clonal lymphocytes - all look the same

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5
Q

what are eosinophils responsible for

A

allergic reactions, parasitic inf, tumors (hodgekins disease)

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6
Q

what doe eosinophils look like

A

bi lobed nuclei (blue) with red granules)

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7
Q

what are mast cells and what are they responsible for

A

large cells containing lots of granules, responsible for allergic reactions

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8
Q

what is the histop of sq cell carcinomas

A

keratin producing
have intercelular bridges
dont form glands

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9
Q

where do sq cell carcinomas forms

A
lung
head/neck
oesophagus
anus
vagina
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10
Q

what is the p40 stain used for

A

lung sq cell C

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11
Q

histopath of adenocarcinomas

A

form glands that secrete

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12
Q

how do you differentiate between an adenocarcinoma and a Sq cell carcinoma

A

mucin stain

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13
Q

what does a transitional cell carcinoma look like

A

just like transitional epithelium

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14
Q

what is known as the general stain

A

papanicolaou

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15
Q

what is the stain for melanin

A

fantana (+ve)

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16
Q

what is the stain for iron (haemachromatosis)

A

prussian blue stain

17
Q

what is the stain for amyloid

A

congo red stain (-> apple green birefringence)

18
Q

what does hematoxylin stain

A

stains the basic (high PH) parts purple/blue

19
Q

what does eosin stain

A

stains acidic parts red/pink

20
Q

what is the lymphoid marker

A

CD45

21
Q

what is the marker for epithelial cells

A

cytokeratins

22
Q

what is the marker for neuroendocrine cells

A

chemogranin stain