Non-neoplastic Bone Disease

Question 1

presentation of Gout

Answer 1

hot, swollen, red v painfull joint

Question 2

most common joints affected in Gout

Answer 2

1st MTP (podogra) or knee

Question 3

inv findings in Gout

Answer 3

neg birefrigent, needle shape urate crystals

Question 4

causes of gout and typical patient

Answer 4

middle aged male

inc purine intake, ETOH, diuretics, metab abn

Question 5

treatment for gout

Answer 5

acute = colchicine

long term = allopurinol

Question 6

inv findings in pseudogout

Answer 6

+ve birefridgement, rhomus shaped Ca pyrophosphate crystals

Question 7

presentation and common joints affected in pseudogout

Answer 7

hot join (knee/shoulder) with effusion 
in 50yr +

Question 8

causes of pseudogout

Answer 8

idiopathic, hyperPTH, DM, hypoThy, wilsons

Question 9

treatment for pseudogout

Answer 9

NSAIDs, intraarticular steroids

Question 10

patho of fracture repair

Answer 10

organisation of haematoma (pro-callous) -> formation of fibrocartelagenous callus -> mineralisation of fibrocartelagenous callus -> remodelling along weight bearing lines

Question 11

what is osteomyelitis

Answer 11

haematogenous spread of local inf

Question 12

causes of osteomyelitis in adults and sites

Answer 12

S Aureus - vertebra, jaw, toes

Question 13

causes and site of osteomyelitis in children

Answer 13

H. Influenza, Group B strep - long bones

Question 14

sympto and X ray of osteomyelitis

Answer 14

generally unwell, pain/swelling/tenderness

X-ray - lytic destruction of bone

Question 15

xray findings in osteoarth

Answer 15

loss of joint space, osteophytes, subchondral sclerosis/cysts
heberdens and bouchards nodes

Question 16

commonly affected sites in osteoarthritis

Answer 16

vertebrae, hips and knees

Question 17

characteristic defects in Rheumatoid arth

Answer 17

radial dev of wrist and ulnar dev of fingers
swan neck and boutonniere fingers
Z shaped thumb
symetrical, slowly progressing