Unit Three Intervertebral Disc Flashcards
How many discs in the spine
23
How many discs in the cervical region
6
How many discs in thoracic region
12
How many discs in the lumbar region
5
Where are there no intervertebral discs in the spine
Occiput -C1, and C1-C2, sacrum and coccyx
What is replaced for disc in sacrum and coccyx
Fibrocartilage with no nucleus
What percentage of the intervertebral disc makes up the height of the spinal column
25%
Where are the discs the thickest
Lumbar
Where are the discs the thinnest
Upper thoracic
Where are the discs thicker ventrally
Cervical and lumbar
What makes up a symphysis joint
2 vertebrae plus the disc
A motion segment is
2 vertebrae plus the disc
What is the intervertebral disc attached to
Vertebral bodies, ALL, PLL, intra-articular, ligaments and ribs 2-9
What are the functions of the disc
Maintain the changeable space between vertebrae, aids in flexibility of spine, acts to properly assimilate compressive loads
The disc gives what type of stability to the vertebral column while the paravertebral muscles provide what type of stability to the spine
Intrinsic with disc and muscles are extrensic
What is considered the largest avascular structure in the human body
Disc
What are the three parts of the disc
Nucleus pulposis, annulus fibrosis, cartilaginous end-plate
The cartilaginous end plate is made up of
Hyaline cartilage
Intervertebral disc allows for what
Compressive, tensile and rotational motion
In between the two bodies contains
Intervertebral disc, end plate and apophyseal ring
The annulus fibrosis is where on the disc
Outer part
The annulus is able to sustain the forces of
Compression, torsion and flexion
Why is the annulus fibrosis able to sustain the forces of compression, torsion, and flexion
Due to the way the rings are located
What are sharpey’s fibers
Fibrous parts of the annulus fibrosis that attaches to the endplates of the vertebral bodies
Water content of the annulus fibrosis at birth is
78%
What is the water content of the annulus fibrosis by age 30
70%
In order for the disc to function properly is must have
High water content
If the disc becomes dehydrated, it loses the ability to
Support the axial load placed on it (loses hydrostatic pressure)
When the disc becomes dehydrated is causes a weight bearing shift which is
Shift from the nucleus, outward onto the annulus and the outer part of the vertebral body, and places more pressure on the Z joints
Weight bearing shift of dehydrated disc can result in
Pathological degenerative disc disease
What holes water in the disc
Proteoglycans, glycoaminoglycans (GAGs)
Function of proteoglycans in disc
Hold 500 times their own weight and gives disc hydrostatic pressure to support axial compression
Over night the height of the disc
Increases up to .5 to 1 inch due to non-axial loading
Diurnal change is
Exchange of water in and out of the disc
Diurnal change is only found in
Non-degenerated discs
How does water move in the disc during the day
Fluid moves out of the nucleus, through the annular rings and into the vertebral body
What happens to hydration of disc at night
Nucleus fills up with fluid and presses against the inner annular fibers and makes more tense and less flexible
Tears in the annular rings occur especially with
Coupled motion of flexion and torsion
How is the distribution of load in the disc
Nucleus distributes load equally throughout the annulus
In the severely degenerated disc, the nucleus has lost all its ability to Cushion the load and causes
Disc herniation
What nerve provides the outer 1/3 of the annular fibers have nociception
Sinuvertebral nerve
Since outer 1/3 of disc has nerve supply, what about other 2/3
No nerves so patient cant tell if damaged or not
How does disc received blood supply
Diffusion through the vertebral body endplates from network of vessels located centrally in endplate
What part of the disc has blood supply
Outer annular fibers
Since outer annulus fibers has blood supply that means
Outer 1/3 of annular fibers will heal/scar
Since inner 2/3 of annular fibers does not have blood supply what does that mean
Do not heal and remains a source of problems after being damaged
How do the rings (lamellae) progressively tear
From center outwards
How does a disc repair itself
From outward in
The nucleus pulposus is what percentage of water at birth
88%
By age 70, the water percentage of nucleus pulposis is what
69 to 70%
What part of the nucleus pulposis comes from the embryonic notochord
Center part of the nucleus
How long does the nucleus pulposis have a direct blood supply
Until age 8 then becomes avascular
Permanent dehydration of the nucleus pulposis occurs through
Aging process
Until what age is the nucleus pulposis disc fully hydrated
Age 40
By what age does the nucleus pulposis disc have reached their maximum state of dehydration
Age 60
The maximum state of dehydration of the nucleus pulposis causes
Decrease ROM and a slight narrowing of the IVF
What makes up about 40% of the total disc
Nucleus pulposus
Where is the nucleus pulposus best developed
Lumbar spine then cervical spine then the thoracic spine
Where is the nucleus pulposis placed in the cervical disc
Centrally
Where is the nucleus pulposis placed in the lumbar disc
Posterior
The composition of the nucleus polposus is
80% water and solid 20%
The solid portion of the nucleus pulposus is made up of
65% proteoglycans and 17% collagen 2 fibers, small amount of elastin
What are the cells located in the nucleus pulposis
Chondrocytes
The nucleus of the disc receives nutrition from
The blood that is inside the subchondral bone
The fluid that goes in and out of the disc goes to the
Subchondral bone
The nutrition is transferred from the subchondral bone to the fluid through what process
Diffusion
The nutrition then enters the fluid and is transported back into the nucleus where it is received is done by what process
Imbibition
What is imbibition
Absorption of a fluid by a solid body or gel
Is the cartilaginous vertebral end plate part of the bone or the vertebrae
No
How thick is the hyaline cartilage of the vertebral end plate
3 to 4 mm
The cartilaginous portion of the vertebral end plate is what with the annulus
Strongly interwoven into the annulus