Unit 2 Part 3 Flashcards
main function of this system is to transport and carry O2 and food to all the cells, and CO2 and wastes from the cells
circulatory
one of the fluids of the body, made up of water, solutes, and cells
blood
another term for white blood cells
leukocytes
another term for red blood cells
erythrocytes
another term for thrombocytes
platelets
normal blood volume is approx ____
4.73 L
class of WBCs that have granulars, nucleus is segmented
granulocytes (neutrophils, eosinophils, basophils)
class of WBCs that have no granules, nucleus is unsegmented
non-granulocytes (lymphocytes, monocytes)
class of cells formed in the myeloid tissue (bone marrow)
myeloid cells
cells formed in the bone marrow
RBCs
platelets
granular leukocytes (neuts, eos, baso)
non granulocytes formed in the lymphatic tissue (mainly spleen and lymph nodes)
lymphoid cells
most numerous type of WBC
stain with the Wright stain
have 2-3 lobes
granules stain pink
neutrophils
least numerous type of WBC
stain with the Wright stain
have an S shaped nucleus
granules stain black
basophils
two-lobed nucleus
stain with the Wright stain
have two oval lobes (nucleus)
granules stain orange
eosinophils
first WBC to arrive at an infection site
neutrophil
WBC that neutralizes the effects of histamine in allergic reactions and destroy certain parasitic worms
eosinophil
WBC that releases histamines
basophil
second most numerous type of WBC, has one large nucleus
lymphocytes
largest WBC with the longest lifespan, has one nucleus (often with a cleft), and is responsible for general cleanup of the infection site
monocytes
cell responsible for detecting, engulfing and destroying pathogens
macrophage
macrophages are produced through differentiation fo monocytes (t/f)
true
main function of WBC
fight infection through phagocytosis
WBCs pass through several stages starting with a ____ cell before becoming mature WBCs
stem
leukocytosis is a(n) ___ in WBCs
increase
leukopenia is a(n) ___ in WBCs
decrease
high amount of neutrophils usually indicates a ___ infection
bacterial
high amount of lymphocytes usually indicates a ___ infection
viral
another term for red blood cells
erythrocytes
a ____ RBC has no nucleus
mature
there are __ oxygen molecules for every hemoglobin molecule
4
immature RBCs still have the nucleus in them, and are also called ___
reticulocytes (retics)
___ is broken down by the liver, spleen and bone marrow
hemoglobin
normal WBC count is ___ per cubic mL of blood
5000 - 9000 (5.0-9.0 x 10^9/L)
normal RBC count is ___ per cubic mL of blood
4.5 - 5.5 million (4.5-5.5 x 10^12/L)
normal platelet count is ___ per cubic mL of blood
150,000 - 450,000 (150-450 x 10^9/L)
cell fragments formed from megakaryocyte in the bone marrow, have no nucleus
platelets
another term for platelets
thrombocytes
main function of platelets
help in the clotting process
formation of RBCs is also called
erythropoiesis
main function of RBC
transport or carry O2 from lungs to body and CO2 from body to lungs when combined with hgb
a dynamic process whereby blood coagulation is initiated and terminated in a rapid and tightly regulated fashion
hemostasis
3 basic components that regulate hemostasis
vascular wall
platelets
coagulation cascade
constriction of the damaged blood vessels and formation of platelet plug
primary hemostasis
coagulation factors present in the blood interact, forming a fibring meshwork (clot)
secondary hemostasis
4 steps of the Hemostatic Process
- vasoconstriction
- formation of primary platelet plug
- progression of stable clot – hemostatic plug
- fibrinolysis
formation of primary platelet plug happens within ___ seconds of injury
15
initiated by tissue factors, coagulation factors taht are found in tissues not in the blood stream
extrinsic pathway
test used to evaluate extrinsic pathway
prothrombin time (PT/INR)
coagulation factors that involve the bloodstream
intrinsic pathway
test used to evaluate intrinsic pathway
partial thromboplastin time (PTT)
both intrinsic and extrinsic pathways lead to this pathway, in which fibrin is produced to seal off the vessel
common pathway
natural element in our body that prevents clotting
heparin
he process by which fibrin is dissolved
fibrinolysis
how can you stimulate platelets?
bring them in contact with a rough surface
antigens are on/in ___
RBCs
antibodies are on/in ___
plasma
also called the Rh factor
D antigen
disorders of the ___ system:
anemia
embolus
hemophilia
leukemia
polycythemia
multiple myeloma
sickle cell anemia
deep vein thrombosis
phlebitis
thrombocytopenia
thrombus
varicose veins
hemolytic disease of the fetus and newborn
circulatory
lab tests for ___ system:
CBC (#1)
PT/INR
cross match
iron (Fe)/ TIBC
PTT
factor studies
circulatory
most common anemia, caused by a decrease in iron, which is needed for hgb production
iron deficiency anemia
anemia caused by a lack of intrinsic factor in the digestive tract
pernicious anemia
required for the absorption of Vitamin B12, which is necessary for normal maturing of RBCs
intrinsic factor
failure of bone marrow to produce enough RBCs as well as WBCs and platelets is the cause of this anemia
aplastic anemia
anemia caused by an excessive destruction of RBCs, often becuase they are deformed
causes jaundice due to bilirubin buildup in the blood
hemolytic anemia
increased number of RBCs (maybe WBCs and platelets) produced by the bone marrow, blood becomes thick and puts a strain on the heart
polycythemia vera