Tumour Pathology 3

Question 1

Local effects of cancer (benign)

Answer 1

pressure, obstruction

Question 2

Local effects of cancer (malignant)

Answer 2

pressure, obstruction
tisc - ulcer, inf
damaged capillaries - bleeding, haemorrhage, anaemia
pressure on nerves = pain= perineural infiltration

Question 3

systemic effects of cancer (malignant)

Answer 3

secretion of hormones (normal- endocrine gland tumour; abnormal/inappropriate - cancer in non-secretory gland)
paraneoplastic syndromes (affected by hormones and factors in response to tumour e,g, in neuro-/myo-pathy)
weight loss, cachexia (wasting)

Question 4

A systemic/metastatic effect of malignant lung is to produce Inappropriate hormone secretion and they are:

Answer 4

ACTH - Adrenocorticotropic hormone
ADH - Antidiuretic hormone

These shows clinical signs

Question 5

________ screening is a way of detecting cancer early - the scraping of cervical epithelium is taken to look for signs of ________ to prevent it from progressing to squamous carcinoma of cervix.

Answer 5

1. Cervical cancer

2. dysplasia (earliest visual change in malignany)

Question 6

Features of dysplasia includes:

Answer 6

similar to cancer but NO INVASION

Disorganisation of cells: increased nulcear size, abnormal mitotic activity
Grading: high (close to cancer-therapeutic action to low)
NO INVASION

Question 7

Histology of a primary tumour is ususally similar to metastasic tumour in a different site - T or F?

Answer 7

T