Storing and Using Genetic Info Flashcards
Each nucleotide of DNA contains
phosphate, sugar (2-deoxribose), nitrogen containing base
In RNA, sugar = ribose
Purines
adenine (A) and guanine (G)
Pyridimines
thymine (T) and cytosine (C),
2 properties of DNA
semi-conservative (1 parental/1daughter) and bidirectional (new strands grow different direction 5 to 3)
Different codons specify the same amino acid
Degeneracy/redundancy of genetic code
coding regions
exons (transcription)
non-coding regions
introns (transcription)
Which chromatin has active genes?
euchromatin
where does transcription occur?
nucleus make mRNA (RNA polymerase)
where does translation occur?
cytoplasm
info contained in mRNA used to make polypeptide
Difference between normal Hb and sickle cell
mutation of single nucleotide
coding strand GAG to GTG
template strand GUG
GLU to VAL (6)
continuous - DNA polymerase
coding strand - 3’ to 5’
template strand - 5’ to 3’
Lagging strand
One gene can code more than 1 protein
alternative splicing