Mutations and Genetic Analysis

Question 1

Translocation - pieces of chromosomes rearranged but no genetic material is gained or lost in the cell.

Answer 1

Balanced Translocation

Question 2

Exchange of chromosome material is unequal resulting in extra or missing genes

Answer 2

Unbalanced Translocation

Question 3

Only acrocentric chromosomes affected in this translocation

Answer 3

Robertsonian Translocation

Question 4

Name acrocentric chromosomes

Answer 4

13,14,15,21,22

Question 5

Robertsonian Translocation

Answer 5

45 chromosomes
Two acrocentric chromosomes attach - common 13+14
14+21, 15+22
carrier is healthy
baby healthy if normal chromosome 13 and 14 passed, and if only one translocated (containing 13 and 14 passed)

problem - if translocated and on standalone chromosome passed - baby have extra - trisomy of either 13(patau - miscarry or some may survive) or 14(miscarry)