Autoimmunity Flashcards
1
Q
Autoimmune disease
both organ specific & non-organ specific
A
tissue/organ damage - cellular/humoral immune mech - direct against auto/self-Ag
2
Q
Estrogen is damaging to Tolerance - T or F?
A
True - thus Autoimmune disease higher in women
3
Q
Immune sys avoids producing damaging reactions against self Ag.
A
Tolerance
4
Q
Deletion of autoreactive T + B cells during cell maturation
A
Central tolerance
5
Q
Inhibit the act of autoreactive cells which escape central tolerance
A
Peripheral tolerance
6
Q
Tolerance is one of the cardinal features of adaptive immunity - T or F?
A
True
breakdown of 1 or more tolerance process= autoimmune disease
7
Q
Non-organ specific autoimmune disorders
A
CT disorders
8
Q
Organ specific autoimmune disorders
A
autoimmune endocrine disorder
