Intro to Fungi Flashcards

1
Q

Fungi gets __ from breaking down __ chemo-organotrophic eukaryote
Lacks _____ and forms ____

A
  1. energy
  2. chemicals
  3. chlorophyll
  4. spores

Cell wall - polysaccharides, chitin or cellulose
Membrane - ergosterol(major sterol)

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2
Q

Classification is based on

A

morphology

major types as moulds, yeasts or mushrooms

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3
Q

Fungi that favour a unicellular habit

A

yeast

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4
Q

Fungi are a significant cause of

A

non-fatal diseases

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5
Q

Epidermophyton causes

A

athlete’s foot

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6
Q

Thrush is caused by

A

Candida spp.

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7
Q

pityriasis versicolor is caused by …….. They can form …..

A

Malassezia spp. (yeast)

hyphae

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8
Q

Microsporum causes

A

athlete’s foot

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9
Q

Trichophyton causes

A

athlete’s foot (mould)

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10
Q

Dermatophytes are _____ which can cause infections of the skin, hair, and nails due to their ability to utilize _____ . They also have the ability to form …..

A

moulds
keratin
hyphae

ringworm inf
tinea …..

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11
Q

Epidermophyton, Microsporum and Trichophyton are _____ and cause

A
Dermatophytosis
athlete foots (mould)
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12
Q

______species infect deep organs of patients with immune dysfunction, e.g. after abdominal surgery, burns, etc. (cases often in ICU)

A

Candida (yeast)

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13
Q

______ spp. infect deep organs of patients undergoing e.g. chemotherapy, stem cell transplantation

A

Aspergillus (mould)

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14
Q

_____ contributes to pathogenicity of fungal inf

A

Host factors

environment, broad spect anti-biotic, immune suppression (disease , iatrogenesis or both)

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15
Q

Which candida sp. have hyphae? What colour colony do they form in chrom agar?

A

C. albicans (mainly oral)

Green

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16
Q

Candida in vagina is caused by …… and shows up …… in selective chrom agar

A

Tropicalis

Blue

17
Q

Candida in skin is caused by …… and shows up …… in selective chrom agar

A

C. glabrata

pink

18
Q

Candida in nails is caused by …… and shows up …… in selective chrom agar

A

C.Krusei

white

19
Q

Candida reside in GI as a commensal flora and most infection are ……..

A

endogenous

20
Q

Candida infection are mostly superficial (nails, skin etc.) and some are disseminated - these types are called……

A

Deep seated - occurs in immuno-compromised

21
Q

Spore formation occurs in …

22
Q

Chronic mucocutaneous candida inf occurs in ……. and the disease is called ………..

A

endocrine and immune dys patients

APECED (autoimmune polyendocrinopathy-candidiasis ectodermal dystrophy

23
Q

Aspergillus (mould) is present in environment and inhalation of ……. can cause disease. It is …. as it can penetrate the blood vessel walls

A

conidia

angioinvasive

24
Q

Asp fumigatus causes

A

simple asthma

25
Asp flavus causes
asthma with eosinophilia
26
Invasive pulmonary aspergillus could cause ........ malignancy
haematological
27
Cryptococcus (yeast) falls under..... group
Basidiomycetes
28
Cryptococcus neoformans causes ......... cryptococcosis
pulmonary
29
Cryptococcus gattii cause
meningitis - esp in patients with AIDS
30
.............. stain is used for direct smear e.g. vaginal
PAS (periodic acid schiff)
31
Common diagnostic is histopath and high-resolution ......
CT scan e.g. Dermatophytes in skin scales (KOH prep)
32
Echinocandins
bind to ergosterols in cell wall
33
Polyenes
target membrane
34
Azoles
inhibit ergosterols syn
35
Allylamines
inhibit ergosterols syn