Tubular Diseases Flashcards

1
Q
A
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2
Q

Etiology of Acute Tubulointerstitial Nephritis

A
  • Drugs
  • Systemic Disease
  • Infections
  • Idiopathic
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3
Q

Etiology of Acute Tubulointerstitial Nephritis

  • Drugs
A
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4
Q

Etiology of Acute Tubulointerstitial Nephritis

  • Most Common Causes
  • Most Common Specific Cause
A

DRUGS (MOST COMMON)

  • Antibiotics (most important) e.g., β-lactams (methicillin) - Sulfonamides
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5
Q

Etiology of Acute Tubulointerstitial Nephritis

  • Systemic Diseases
A

① Sarcoidosis.
② Sjögren’s disease.
③ Systemic lupus erythematosus (SLE).

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6
Q

Dx of Acute Tubulointerstitial Nephritis

A
  • Hx
  • Labs
  • Bx
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7
Q

Dx of Acute Tubulointerstitial Nephritis

  • Hx
A

HISTORY OF :
▪ Drug intake
▪ Exposure to toxic substance
▪ Infection.

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8
Q

Dx of Acute Tubulointerstitial Nephritis

  • Labs
A
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9
Q

Dx of Acute Tubulointerstitial Nephritis

  • Bx
A
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10
Q

managment of Acute Tubulointerstitial Nephritis

A
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11
Q

Management of Acute Tubulointerstitial Nephritis

  • Algorithm
A
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12
Q

etiology of Acute Pyelonephritis

A
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13
Q

etiology of Acute Pyelonephritis

  • Organisms
A
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14
Q

Risk Factors for Acute Pyelonephritis

  • Impaired Urine Flow
A

▪ Anatomical abnormalities (as vesico-ureteric reflux - ureteric stricture).

▪ Renal stones.

▪ Senile prostatic enlargement and bladder neck obstruction.

▪ Neurogenic bladder (leads to residual urine in the bladder and stasis).

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15
Q

Complications of Acute Pyelonephritis

A
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16
Q

INVx for Acute Pyelonephritis

A
  • urinalysis
  • Urine culture / susceptibilities
  • Blood Culture
  • KFTs
  • Imaging
17
Q

INVx for Acute Pyelonephritis

  • Urinalysis
A
18
Q

INVx for Acute Pyelonephritis

  • Urine Culture
A
19
Q

Causes of sterile pyuria (pus cells with negative repeated cultures)

A
20
Q

INVx for Acute Pyelonephritis

  • Blood Culture
A

21
Q

INVx for Acute Pyelonephritis

  • KFTs
A

Renal dysfunction could be a preceding event or a complication of pyelonephritis.

22
Q

INVx for Acute Pyelonephritis

  • Imaging
A
23
Q

Management of Acute Pyelonephritis

A