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Medicine II - OSCE > Peripheral Neuropathy > Flashcards

Peripheral Neuropathy Flashcards

1
Q
A
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2
Q

Classification of Peripheral Neuropathy

A
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3
Q

Causes of Mononeurpathy & Mononeuropathy Multiplex

A
  • Traumatic
  • Infective
  • Vascular
  • Metabolic
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4
Q

Causes of Mononeurpathy & Mononeuropathy Multiplex

  • Traumatic
A
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5
Q

Causes of Mononeurpathy & Mononeuropathy Multiplex

  • Infective
A
  1. Leprosy
  2. Herpes Zoster
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6
Q

Causes of Mononeurpathy & Mononeuropathy Multiplex

  • Vascular
A

Polyarteritis Nodosa

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7
Q

Causes of Mononeurpathy & Mononeuropathy Multiplex

  • Metabolic
A

DM

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8
Q

Causes of Polyneuropathy

A
  • Heredofamilial
  • Acquired
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9
Q

Causes of Polyneuropathy

  • Heredo-Familial
A
  • Peroneal muscle atrophy.
  • Hypertrophic interstitial polyneuropathy.
  • Refsum disease.
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10
Q

Causes of Polyneuropathy

  • Acquired
A
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11
Q

Acquired Causes of Polyneuropathy

  • Infective
A
  • Viral: mumps, measles.
  • Bacterial: Typhus, Typhoid, Tetanus.
  • Mycobacterial: Leprosy.
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12
Q

Acquired Causes of Polyneuropathy

  • Toxic
A
  • Inorganic: lead, copper, arsenic, antimony, gold. (Heavy metals).
  • Organic: alcohol, insecticides.
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13
Q

Acquired Causes of Polyneuropathy

  • Metabolic & Endocrine
A

Diabetes mellitus, uremia, amyloidosis, acromegaly, myxedema.

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14
Q

Acquired Causes of Polyneuropathy

  • Nutritional
A

Pellagra, Beri-Beri, subacute combined degeneration.

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15
Q

Acquired Causes of Polyneuropathy

  • Iatrogenic
A

Isoniazid, sulphonamides, phenytoin, vincristine.

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16
Q

Acquired Causes of Polyneuropathy

  • Autoimmune
A

Guillain Barre Syndrome, collagen vascular disorders.

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17
Q

Acquired Causes of Polyneuropathy

  • Paraneoplastic
A

Bronchogenic carcinoma, lymphoma.

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18
Q

Pathology of Axonal Neuropathy

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19
Q

Pathology of Demyelinating Neuropathy

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20
Q

CP of Polyneuropathy

  • General
A
  • Bilateral
  • Symmetrical
  • Distal more than Proximal
  • Lower Limbs earlier than Upper Limbs.
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21
Q

CP of Polyneuropathy

  • Sensory
22
Q

CP of Polyneuropathy

  • Motor
23
Q

CP of Polyneuropathy

  • Autonomic
24
Q

Investigations for Polyneuropathy

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Investigations for **Polyneuropathy** - NCS
- Reduced nerve conduction velocity
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Investigations for **Polyneuropathy** - Nerve Bx
- usually the Sural Nerve
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Investigations for **Polyneuropathy** - Detect the cause
- Blood sugar - Tests for collagen vascular disorders - S. creatinine
28
Types of **Diabetic Neuropathy**
- Diabetic Sensorimotor Polyneurtopathy - Diabetic Autonomic Neuropathy - Diabetic Proximal Neuropathy (Diabetic Amyotrophy) - Diabetic Mononeuropathy - Diabetic Truncal Neuropathy
29
**Diabetic Sensorimotor Polyneuropathy** is common in
Type I DM
30
CP of **Diabetic Sensorimotor Polyneuropathy**
31
Pathogenesis of **Diabetic Sensorimotor Polyneuropathy**
- Hyperglycemia will cause sorbitol accumulation → decreased myoinositol uptake by nerve Fibers ----> impaired impulse conduction.
32
Another Name of **Diabetic Proximal Polyneuropathy**
Diabetic Amyotrophy
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**Diabetic Proximal Polyneuropathy** is common in ......
Type II DM
34
CP of **Diabetic Proximal Polyneuropathy**
35
CP of **Diabetic Mononeuropathy**
36
CP of **Diabetic Truncal Neuropathy**
- Recurrent attacks of truncal pain with sensory deficit in the distribution of a single thoracic root. - Spontaneous recovery occurs in few months..
37
TTT of **Diabetic Neuropathy**
38
Another Name of **Guillian-Barre Syndrome**
Acute Post Infective Polyradiculoneuropathy
39
Etiology of **Guillian-Barre Syndrome**
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CP of **Guillian-Barre Syndrome**
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CP of **Guillian-Barre Syndrome** - Motor
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CP of **Guillian-Barre Syndrome** - Sensory
Glove and stocking hypoesthesia
43
Prognosis of **Guillian-Barre Syndrome**
- Recovery in 3-6 months. - May be with mild residue in 40% of cases. - Survival for 8 weeks carries a good prognosis.
44
Investigations for **GBS**
45
TTT of **GBS**
46
TTT of **GBS** - NGT
feeding for bulbar palsy.
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TTT of **GBS** - Assissted Ventilation
...
48
TTT of **GBS** - SC Heparin
to guard against deep venous thrombosis (DVT).
49
TTT of **GBS** - Plasmapheresis
must be done in the first 2 weeks
50
TTT of **GBS** - IVIG
0.4 g/Kg / day for 5 successive days.

Medicine II - OSCE (32 decks)

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