Tu - Colon cancer diagnostics for targeted therapy and immunotherapy

Question 1

Which medication are tumor cellines with 11q deletion sensitive to?

Answer 1

Prexasertib

Question 2

What do the most prominent homozygous deletions in cancer affect? What do they eliminate? (specific)

Answer 2

Affect chromosome 9p21.3 and eliminate CDKN2A/B tumor suppressors