Mo - Oncolytic viruses and immune modulation of the tumor microenvironment Flashcards

1
Q

What is a neoantigen?

A

Antigens in the tumors that derive from mutations in the DNA. It is seen as an antigen that has never been seen before by the immune system.

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2
Q

Why is it important for GSK3B to be active?

A

Because then you get less immature dendritic cells and more T cells to fight the tumor

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3
Q

In which form (unphosphorylated/phosphorylated) is GSK3B active?

A

Unphosphorylated

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