Fr - Radiobiology

Question 1

What are the 6 Rs, the hallmarks of radiobiology?

Answer 1

• Radiosensitivity
• Repair/recovery of DNA
• Re oxygenation of hypoxic cells
• Redistribution
• Repopulation
• Reactivation of the immune response

Question 2

What do the 6 Rs stand for? (explain complicated) (3)

Answer 2

Six phenomena which determine the treatment efficacy of radiotherapy in the clinic:
The complication rate (by normal tissue cell injury) and
tumour control rate (by tumour cell kill), Processes which can be modulated.